Coronary artery calcium and intima-media thickness are associated with level of cytomegalovirus immunoglobulin G in HIV-infected patients

被引：15
|
作者：
Knudsen, A. [1 ,2 ,3 ]
Kristoffersen, U. S. [2 ,3 ]
Panum, I. [4 ]
Hansen, Y. B. [5 ]
Skottrup, P. D. [6 ,7 ]
Hasbak, P. [2 ]
Kjaer, A. [2 ,3 ]
Lebech, A-M [1 ,8 ]
机构：
[1] Copenhagen Univ Hosp, Dept Infect Dis, Kettegaard Alle 30, DK-2650 Hvidovre, Denmark
[2] Rigshosp, Copenhagen Univ Hosp, Dept Clin Physiol Nucl Med & PET, Copenhagen, Denmark
[3] Univ Copenhagen, Dept Biomed Sci, Cluster Mol Imaging, Copenhagen, Denmark
[4] Copenhagen Univ Hosp, Dept Clin Microbiol, Hvidovre, Denmark
[5] Copenhagen Univ Hosp, Dept Clin Biochem, Glostrup, Denmark
[6] Copenhagen Univ Hosp, Dept Clin Biochem, Hvidovre, Denmark
[7] Novo Nordisk AS, Res Bioanal, Malov, Denmark
[8] Rigshosp, Copenhagen Univ Hosp, Dept Infect Dis, Copenhagen, Denmark
来源：
HIV MEDICINE | 2019年 / 20卷 / 01期
基金：
英国医学研究理事会;
关键词：
atherosclerosis; cardiovascular disease; coronary artery calcium; cytomegalovirus; HIV infection; DISEASE;
D O I：
10.1111/hiv.12672
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Coinfection with cytomegalovirus (CMV) may be involved in cardiovascular disease in HIV-infected patients. We found that higher level of CMV immunoglobulin G (IgG) was independently associated with an increased risk of coronary artery calcium and higher intima-media thickness in HIV-infected patients but not in healthy controls after adjustment for other cardiovascular risk factors and levels of herpes viridae IgG.
引用
收藏
页码：60 / 62
页数：3
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