The Landscape of Alteration of DNA Integrity-Related Genes and Their Association with Tumor Mutation Burden in Non-Small Cell Lung Cancer

被引：0
|
作者：
Sharpnack, M. [1 ]
Cho, J. H. [2 ]
Oezkan, F. [2 ]
Koenig, M. [1 ]
Kim, I. [3 ]
Otterson, G. [2 ]
Huang, K. [4 ]
Carbone, D. [2 ]
He, K. [2 ]
机构：
[1] Ohio State Univ, Columbus, OH 43210 USA
[2] Ohio State Univ, Comprehens Canc Ctr, Dept Med, Columbus, OH 43210 USA
[3] Univ Calif San Francisco, Dept Surg, San Francisco, CA 94143 USA
[4] Ohio State Univ, Dept Biomed Informat, Columbus, OH 43210 USA
来源：
JOURNAL OF THORACIC ONCOLOGY | 2017年 / 12卷 / 11期
关键词：
Mutation burden; DNA integrity; NSCLC;
D O I：
10.1016/j.jtho.2017.09.435
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
OA 18.02
引用
收藏
页码：S1795 / S1796
页数：2
相关论文
共 50 条
  • [21] The Association Between Tumor Burden and the Efficacy of Immunotherapy Among Patients With Non-small Cell Lung Cancer
    Hui, Jia-Jun
    Yan, Han-Lu
    Ding, Sheng-Jun
    Qin, Bao-Dong
    Jiao, Xiao-Dong
    Zang, Yuan-Sheng
    CANCER CONTROL, 2025, 32
  • [22] DNA damage response and repair pathway alteration and its association with tumor mutation burden and platinum-based chemotherapy in small cell lung cancer
    Park, Sehhoon
    Lee, Hayoon
    Lee, Boram
    Sun, Jong-Mu
    Park, Woong-Yang
    Ahn, Jin Seok
    Ahn, Myung-Ju
    Lee, Se-Hoon
    Park, Keunchil
    CANCER RESEARCH, 2019, 79 (13)
  • [23] Tumor volume as a predictor of cell free DNA mutation detection in advanced non-small cell lung cancer
    Haseltine, Justin M.
    Offin, Michael
    Flynn, Jessica R.
    Zhang, Zhigang
    Lebow, Emily S.
    Aziz, Khaled
    Makhnin, Alex
    Eichholz, Jordan
    Lim, Lee P.
    Li, Mark
    Isbell, James M.
    Gomez, Daniel R.
    Li, Bob T.
    Rimner, Andreas
    TRANSLATIONAL LUNG CANCER RESEARCH, 2022, : 1578 - 1590
  • [24] Tumor mutation burden in non-small cell lung cancer: real world data from the routine lab
    Falk, M.
    Schatz, S.
    Jori, B.
    Menon, R.
    Griesinger, F.
    Ramdani, H.
    Heukamp, L.
    Tiemann, M.
    ONCOLOGY RESEARCH AND TREATMENT, 2019, 42 : 107 - 108
  • [25] The clinical utility of tumor mutational burden in non-small cell lung cancer
    Greillier, Laurent
    Tomasini, Pascale
    Barlesi, Fabrice
    TRANSLATIONAL LUNG CANCER RESEARCH, 2018, 7 (06) : 639 - 646
  • [26] Tumor Mutation Burden Correlates With Efficacy of Chemotherapy/Targeted Therapy in Advanced Non-Small Cell Lung Cancer
    Lin, Chen
    Shi, Xun
    Zhao, Jun
    He, Qiong
    Fan, Yun
    Xu, Weizhen
    Shao, Yang
    Yu, Xinmin
    Jin, Ying
    FRONTIERS IN ONCOLOGY, 2020, 10
  • [27] Clinical and genomic features of high tumor mutation burden in patients with non-small cell lung cancer.
    Qiu, Yuan
    Yang, Haihong
    Chen, Hanzhang
    Deng, Qiuhua
    Liu, Liping
    Xiao, Dakai
    Shao, Di
    Li, Weiwei
    Jiang, Wenxi
    Zhu, Changbin
    Lin, Yongping
    He, Jianxing
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [28] Circulating Tumor DNA for Mutation Detection and Identification of Mechanisms of Resistance in Non-Small Cell Lung Cancer
    Yeung, Kay T.
    More, Soham
    Woodward, Brian
    Velculescu, Victor
    Husain, Hatim
    MOLECULAR DIAGNOSIS & THERAPY, 2017, 21 (04) : 375 - 384
  • [29] Circulating Tumor DNA for Mutation Detection and Identification of Mechanisms of Resistance in Non-Small Cell Lung Cancer
    Kay T. Yeung
    Soham More
    Brian Woodward
    Victor Velculescu
    Hatim Husain
    Molecular Diagnosis & Therapy, 2017, 21 : 375 - 384
  • [30] The positive correlation between tumor mutation burden and the purity of tumor samples in non-small cell lung cancer and colorectal cancer.
    Tong, Jian
    Zhang, Xiaoni
    Qu, Hongyue
    Yang, Qing
    Duan, Jingxian
    Xu, Mingyan
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
12345