From Mice to Men Commonalities in Physiology for Stem Cell-Based Cardiac Repair

被引:6
|
作者
Penn, Marc S. [1 ]
Anwaruddin, Saif [1 ]
Nair, Ravi [1 ]
Ellis, Stephen [1 ]
机构
[1] Cleveland Clin, Inst Heart & Vasc, Ctr Cardiovasc Cell Therapy, Skirball Lab Cardiovasc Cellular Therapeut, Cleveland, OH 44195 USA
关键词
myocardial infarction; allogeneic; mesenchymal stem cells; magnetic resonance imaging; echocardiography; ACUTE MYOCARDIAL-INFARCTION; ISCHEMIC CARDIOMYOPATHY; REGENERATION; THERAPY; EXPRESSION; TRIAL;
D O I
10.1016/j.jacc.2009.06.054
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Current treatments for acute myocardial infarction (AMI) involving successful restoration of blood flow into the infarct-related artery either by percutaneous methods or by fibrinolytic therapy have shown to be of benefit in reduction of short-term mortality. While the advantages of these reperfusion strategies are well established, they do not address the loss of myocardium and adverse remodeling that occurs.
引用
收藏
页码:2287 / 2289
页数:3
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