Oncometabolite-Independent Anti-Apoptotic Feature Via Phospholipid Metabolic Adaptation in IDH2 Mutant AML Cells

被引：0
|
作者：
Morishima, Tatsuya [1 ,2 ]
Takahashi, Koichi [3 ,4 ]
Chin, Desmond Wai Loon [5 ]
Tokunaga, Kenji [6 ]
Arima, Yuichiro [7 ]
Matsuoka, Masao [6 ]
Suda, Toshio [5 ,8 ]
Takizawa, Hitoshi [2 ]
机构：
[1] Kumamoto Univ, Int Res Ctr Med Sci, Lab Hematopoiet Stem Cell Engn, Kumamoto, Japan
[2] Kumamoto Univ, Int Res Ctr Med Sci, Lab Stem Cell Stress, Kumamoto, Japan
[3] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX USA
[4] Univ Texas MD Anderson Canc Ctr, Dept Genom Med, Houston, TX USA
[5] Natl Univ Singapore, Canc Sci Inst Singapore, Singapore, Singapore
[6] Kumamoto Univ Hosp, Dept Hematol Rheumatol & Infect Dis, Kumamoto, Japan
[7] Kumamoto Univ, Int Res Ctr Med Sci, Lab Dev Cardiol, Kumamoto, Japan
[8] Kumamoto Univ, Int Res Ctr Med Sci, Lab Stem Cell Regulat, Kumamoto, Japan
来源：
BLOOD | 2022年 / 140卷
关键词：
D O I：
10.1182/blood-2022-162976
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：3012 / 3013
页数：2
相关论文
共 34 条
  • [21] Upregulation of MIR-132-5P via nicotine enhances cell survival in PC12 cells by targeting the anti-apoptotic protein BCL-2
    Shrestha, T.
    Takahashi, T.
    Li, C.
    Matsumoto, M.
    Maruyama, H.
    JOURNAL OF THE NEUROLOGICAL SCIENCES, 2019, 405
  • [22] Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5′-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells
    Barbour, Suzanne E.
    Nguyen, Phuong T.
    Park, Margaret
    Emani, Bhargavi
    Lei, Xiaoyong
    Kambalapalli, Mamatha
    Shultz, Jacqueline C.
    Wijesinghe, Dayanjan
    Chalfant, Charles E.
    Ramanadham, Sasanka
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 290 (17) : 11021 - 11031
  • [23] COX-2 expression induced by CD40 engagement in mesenchymal cells associated with gastric cancer is involved in angiogenesis via VEGF and CCR2 upregulation and the anti-apoptotic effect
    Futagami, S
    Hiratsuka, T
    Tatsuguchi, A
    Shindo, T
    Hamamoto, T
    Ueki, N
    Kusunoki, M
    Shinji, Y
    Shinoki, K
    Suzuki, K
    Wada, K
    Gudis, K
    Miyake, K
    Tsukui, T
    Sakamoto, C
    GASTROENTEROLOGY, 2005, 128 (04) : A349 - A349
  • [24] Processed Panax ginseng, Sun Ginseng, Decreases Oxidative Damage Induced by tert-butyl Hydroperoxide via Regulation of Antioxidant Enzyme and Anti-apoptotic Molecules in HepG2 Cells
    Lee, Hyejin
    Kim, Jinhee
    Lee, Seo Young
    Park, Jeong Hill
    Hwang, Gwi Seo
    JOURNAL OF GINSENG RESEARCH, 2012, 36 (03) : 248 - 255
  • [25] The anti-apoptotic effect of IGF-1 on tissue resident stem cells is mediated via PI3-kinase dependent secreted frizzled related protein 2 (5firp2) release
    Gehmert, Sebastian
    Sadat, Sanga
    Song, Yao-Hua
    Yan, Yasheng
    Alt, Eckhard
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 371 (04) : 752 - 755
  • [26] HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins
    Jacobs, Aaron T.
    Marnett, Lawrence J.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (14) : 9176 - 9183
  • [27] Nickel compounds render anti-apoptotic effect to human bronchial epithelial Beas-2B cells by induction of cyclooxygenase-2 through an IKKβ/p65-dependent and IKKα- and p50-independent pathway
    Ding, Jin
    Zhang, Xinhai
    Li, Jingxia
    Song, Lun
    Ouyang, Weiming
    Zhang, Dongyun
    Xue, Caifang
    Costa, Max
    Melendez, J. Andres
    Huang, Chuanshu
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (51) : 39022 - 39032
  • [28] Ethyl acetate extract of Patrinia scabiosaefolia downregulates anti-apoptotic Bcl-2/BCI-XL expression, and induces apoptosis in human breast carcinoma MCF-7 cells independent of caspase-9 activation
    Chiu, LCM
    Ho, TS
    Wong, EYL
    Ooi, VEC
    JOURNAL OF ETHNOPHARMACOLOGY, 2006, 105 (1-2) : 263 - 268
  • [29] M3-mAChR Stimulation Exerts Anti-apoptotic Effect Via Activating the HIF-1α/HO-1/VEGF Signaling Pathway in H9c2 Rat Ventricular Cells
    Hui, Yang
    Zhao, Yanli
    Ma, Ning
    Peng, Yahui
    Pan, Zhenwei
    Zou, Chaoxia
    Zhang, Pengxia
    Du, Zhimin
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2012, 60 (05) : 474 - 482
  • [30] The ADP-ribosylating CTA1-DD adjuvant enhances T cell-dependent and independent responses by direct action on B cells involving anti-apoptotic bcl-2-and germinal center-promoting effects
    Ågren, L
    Sverremark, E
    Ekman, L
    Schön, K
    Löwenadler, B
    Fernandez, C
    Lycke, N
    JOURNAL OF IMMUNOLOGY, 2000, 164 (12): : 6276 - 6286
1234