Pomegranate Protection against Cardiovascular Diseases

被引：34
|
作者：
Aviramand, Michael [1 ]
Rosenblat, Mira
机构：
[1] Technion Israel Inst Technol, Rappaport Family Inst Res Med Sci, Lipid Res Lab, Fac Med, IL-31096 Haifa, Israel
来源：
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2012年 / 2012卷
关键词：
LOW-DENSITY-LIPOPROTEIN; INTIMA-MEDIA THICKNESS; CORONARY-HEART-DISEASE; JUICE PJ CONSUMPTION; KAPPA-B ACTIVATION; E-O MICE; OXIDATIVE STRESS; ATHEROSCLEROTIC MICE; ANTIOXIDANT ACTIVITY; LIPID-PEROXIDATION;
D O I：
10.1155/2012/382763
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
The current paper summarizes the antioxidative and antiatherogenic effects of pomegranate polyphenols on serum lipoproteins and on arterial macrophages (two major components of the atherosclerotic lesion), using both in vitro and in vivo humans and mice models. Pomegranate juice and its by-products substantially reduced macrophage cholesterol and oxidized lipids accumulation, and foam cell formation (the hallmark of early atherogenesis), leading to attenuation of atherosclerosis development, and its consequent cardiovascular events.
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页数：20
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