The Th1/Th2 paradigm and the allograft response

被引：224
|
作者：
Strom, TB [1 ]
RoyChaudhury, P [1 ]
Manfro, R [1 ]
Zheng, XX [1 ]
Nickerson, PW [1 ]
Wood, K [1 ]
Bushell, A [1 ]
机构：
[1] UNIV OXFORD,JOHN RADCLIFFE HOSP,NUFFIELD DEPT SURG,OXFORD OX3 9DU,ENGLAND
来源：
CURRENT OPINION IN IMMUNOLOGY | 1996年 / 8卷 / 05期
关键词：
D O I：
10.1016/S0952-7915(96)80087-2
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Although Th1- and Th2-type cytokine profiles have been associated with rejection and tolerance respectively, this paradigm may not be completely accurate. Instead, recent studies suggest that there could be a hierarchy of T-cell growth factors with regard to their ability to block tolerance and induce rejection (rather than a polarized Th1/Th2 demarcation).
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页码：688 / 693
页数：6
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