Vitamin D and multiple sclerosis

被引：43

作者：

Hewer, Sarah ^{[1
]}

Lucas, Robyn ^{[2
]}

van der Mei, Ingrid ^{[3
]}

Taylor, Bruce V. ^{[3
]}

机构：

[1] Royal Hobart Hosp, Dept Neurol, Hobart, Tas, Australia

[2] Australian Natl Univ, Natl Ctr Epidemiol & Populat Hlth, Canberra, ACT, Australia

[3] Univ Tasmania, Menzies Res Inst Tasmania, Hobart, Tas 7000, Australia

来源：

JOURNAL OF CLINICAL NEUROSCIENCE | 2013年 / 20卷 / 05期

关键词：

Calcitriol; Cholecalciferol; Multiple sclerosis; Vitamin D; ENVIRONMENTAL SUN EXPOSURE; CENTRAL-NERVOUS-SYSTEM; CD4(+) T-CELLS; 1,25-DIHYDROXYVITAMIN D-3; D-RECEPTOR; ULTRAVIOLET-RADIATION; 25-HYDROXYVITAMIN D; RELAPSE RISK; UV-RADIATION; CYP27B1; GENE;

D O I：

10.1016/j.jocn.2012.10.005

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The role of vitamin D supplementation in preventing multiple sclerosis (MS) and/or treating MS progression is an area of significant research interest. We detail the current status of the ongoing research in this field, and note the lack of class I evidence from well-conducted, large, double-blind, placebo-controlled studies of vitamin D supplementation in the prevention and/or treatment of MS. We have been able to provide some guidelines for practitioners based on the substantial burden of supportive evidence for the use of vitamin D in MS as summarised here. These guidelines may provide some support to those clinicians who treat people with MS and their families. Crown Copyright (c) 2012 Published by Elsevier Ltd. All rights reserved.

引用

页码：634 / 641

页数：8

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