Efficient chemical synthesis of oligonucleotides containing the 2-deoxyribonolactone site

被引：3
|
作者：
Kotera, M [1 ]
Bourdat, AG [1 ]
Defrancq, E [1 ]
Jourdan, M [1 ]
Garcia, J [1 ]
Coulombeau, C [1 ]
Lhomme, J [1 ]
机构：
[1] Univ Grenoble 1, CNRS, LEDSS, F-38041 Grenoble 9, France
来源：
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 1999年 / 18卷 / 6-7期
关键词：
D O I：
10.1080/07328319908044705
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A highly efficient synthetic method for incorporation of the deoxyribonolactone lesion into oligonucleotides was developed using the photochemical properties of 7-nitroindole.
引用
收藏
页码：1323 / 1324
页数：2
相关论文
共 50 条
  • [21] Mutagenic effects of 2-deoxyribonolactone in Escherichia coli.: An abasic lesion that disobeys the A-rule
    Kroeger, KM
    Jiang, YL
    Kow, YW
    Goodman, MF
    Greenberg, MM
    BIOCHEMISTRY, 2004, 43 (21) : 6723 - 6733
  • [22] CHEMICAL SYNTHESIS OF SOME OLIGONUCLEOTIDES CONTAINING DEOXYTHYMIDINE AND DEOXYADENOSINE
    WEISS, R
    BIRCHHIRSCHFELD, E
    JOURNAL FUR PRAKTISCHE CHEMIE, 1977, 319 (02): : 333 - 342
  • [23] Synthesis and characterization of oligonucleotides containing a 4′-keto abasic site
    Chen, JY
    Stubbe, J
    BIOCHEMISTRY, 2004, 43 (18) : 5278 - 5286
  • [24] Cross-linking of 2-deoxyribonolactone and its β-elimination product by base excision repair enzymes
    Kroeger, KM
    Hashimoto, M
    Kow, YW
    Greenberg, MM
    BIOCHEMISTRY, 2003, 42 (08) : 2449 - 2455
  • [25] AN APPROACH TO THE SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING 2'-DEOXY-6-THIOGUANOSINE AT A PREDETERMINED SITE
    CHRISTOPHERSON, MS
    BROOM, AD
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1991, 201 : 100 - MEDI
  • [26] Selective Radiation-Induced Generation of 2-Deoxyribonolactone Lesions in DNA Mediated by Aromatic Iodonium Derivatives
    Roginskaya, Marina
    Razskazovskiy, Yuriy
    RADIATION RESEARCH, 2009, 171 (03) : 342 - 348
  • [27] Half-life and DNA strand scission products of 2-deoxyribonolactone oxidative DNA damage lesions
    Zheng, Y
    Sheppard, TL
    CHEMICAL RESEARCH IN TOXICOLOGY, 2004, 17 (02) : 197 - 207
  • [28] Photogeneration of 2-Deoxyribonolactone in Benzophenone-Purine Dyads. Formation of Ketyl-C1′ Biradicals
    Paris, Cecilia
    Encinas, Susana
    Belmadoui, Nourreddine
    Climent, Maria J.
    Miranda, Miguel Angel
    ORGANIC LETTERS, 2008, 10 (20) : 4409 - 4412
  • [29] EFFICIENT SYNTHESIS OF 2'-DEOXYFORMYCIN-A CONTAINING OLIGONUCLEOTIDES AND CHARACTERIZATION OF THEIR STABILITY IN DUPLEX DNA
    KUHN, H
    SMITH, DP
    DAVID, SS
    JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (22): : 7094 - 7095
  • [30] Synthesis of oligonucleotides containing a new azobenzene fragment with efficient photoisomerizability
    Yamana, K
    Kan, K
    Nakano, H
    BIOORGANIC & MEDICINAL CHEMISTRY, 1999, 7 (12) : 2977 - 2983
12345