Airborne olive pollen counts are not representative of exposure to the major olive allergen Ole e 1

被引：83

作者：

Galan, C. ^{[1
]}

Antunes, C. ^{[2
,3
]}

Brandao, R. ^{[2
]}

Torres, C. ^{[1
]}

Garcia-Mozo, H. ^{[1
]}

Caeiro, E. ^{[2
]}

Ferro, R. ^{[2
]}

Prank, M. ^{[4
]}

Sofiev, M. ^{[4
]}

Albertini, R. ^{[5
]}

Berger, U. ^{[6
]}

Cecchi, L. ^{[7
]}

Celenk, S. ^{[8
]}

Grewling, L. ^{[9
]}

Jackowiak, B. ^{[9
]}

Jaeger, S. ^{[6
]}

Kennedy, R. ^{[10
]}

Rantio-Lehtimaki, A. ^{[11
]}

Reese, G. ^{[12
]}

Sauliene, I. ^{[13
]}

Smith, M. ^{[6
]}

Thibaudon, M. ^{[14
]}

Weber, B. ^{[12
]}

Weichenmeier, I. ^{[15
,16
]}

Pusch, G. ^{[15
,16
]}

Buters, J. T. M. ^{[15
,16
]}

机构：

[1] Univ Cordoba, CeiA3, Dept Bot Ecol & Plant Physiol, Cordoba, Spain

[2] Univ Evora, ICAAM Inst Mediterranean Crop & Environm Sci, Evora, Portugal

[3] Univ Coimbra, Ctr Neurosci & Cell Biol CNC, Coimbra, Portugal

[4] Finnish Meteorol Inst, FIN-00101 Helsinki, Finland

[5] Univ Parma, Univ Hosp Parma, UO Med Immunol, Lab Allergol,Dept Clin & Expt Med, I-43100 Parma, Italy

[6] Med Univ Vienna, Res Unit Aerobiol & Pollen Informat, Dept Otorhinolaryngol, Vienna, Austria

[7] Univ Florence, Interdept Ctr Bioclimatol, Florence, Italy

[8] Uludag Univ, Sci & Arts Fac, Dept Biol, Aerobiol Lab, Gorukle, Turkey

[9] Adam Mickiewicz Univ, Fac Biol, Lab Aeropalynol, Poznan, Poland

[10] Univ Worcester, Natl Pollen & Aerobiol Res Unit, Worcester, England

[11] Univ Turku, Aerobiol Unit, CERUT, Turku, Finland

[12] Allergopharma Joachim Ganzer KG, Reinbek, Germany

[13] Siauliai Univ, Dept Environm Res, Shiauliai, Lithuania

[14] RNSA, Brussieu, France

[15] Tech Univ Munich, Helmholtz Ctr Munich, ZAUM Ctr Allergy & Environm, D-80802 Munich, Germany

[16] Kuhne Fdn, CK CARE, Munich, Germany

来源：

ALLERGY | 2013年 / 68卷 / 06期

关键词：

allergy; enzyme-linked immunosorbent assay; HIALINE; model; EUROPAEA POLLEN; BIRCH POLLEN; OLE-E-1;

D O I：

10.1111/all.12144

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Pollen is routinely monitored, but it is unknown whether pollen counts represent allergen exposure. We therefore simultaneously determined olive pollen and Ole e 1 in ambient air in Cordoba, Spain, and Evora, Portugal, using Hirst-type traps for pollen and high-volume cascade impactors for allergen. Pollen from different days released 12-fold different amounts of Ole e 1 per pollen (both locations P<0.001). Average allergen release from pollen (pollen potency) was much higher in Cordoba (3.9pg Ole e 1/pollen) than in Evora (0.8pg Ole e 1/pollen, P=0.004). Indeed, yearly olive pollen counts in Cordoba were 2.4 times higher than in Evora, but Ole e 1 concentrations were 7.6 times higher. When modeling the origin of the pollen, >40% of Ole e 1 exposure in Evora was explained by high-potency pollen originating from the south of Spain. Thus, olive pollen can vary substantially in allergen release, even though they are morphologically identical.

引用

页码：809 / 812

页数：4

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