Airborne olive pollen counts are not representative of exposure to the major olive allergen Ole e 1

被引：83

作者：

Galan, C. ^{[1
]}

Antunes, C. ^{[2
,3
]}

Brandao, R. ^{[2
]}

Torres, C. ^{[1
]}

Garcia-Mozo, H. ^{[1
]}

Caeiro, E. ^{[2
]}

Ferro, R. ^{[2
]}

Prank, M. ^{[4
]}

Sofiev, M. ^{[4
]}

Albertini, R. ^{[5
]}

Berger, U. ^{[6
]}

Cecchi, L. ^{[7
]}

Celenk, S. ^{[8
]}

Grewling, L. ^{[9
]}

Jackowiak, B. ^{[9
]}

Jaeger, S. ^{[6
]}

Kennedy, R. ^{[10
]}

Rantio-Lehtimaki, A. ^{[11
]}

Reese, G. ^{[12
]}

Sauliene, I. ^{[13
]}

Smith, M. ^{[6
]}

Thibaudon, M. ^{[14
]}

Weber, B. ^{[12
]}

Weichenmeier, I. ^{[15
,16
]}

Pusch, G. ^{[15
,16
]}

Buters, J. T. M. ^{[15
,16
]}

机构：

[1] Univ Cordoba, CeiA3, Dept Bot Ecol & Plant Physiol, Cordoba, Spain

[2] Univ Evora, ICAAM Inst Mediterranean Crop & Environm Sci, Evora, Portugal

[3] Univ Coimbra, Ctr Neurosci & Cell Biol CNC, Coimbra, Portugal

[4] Finnish Meteorol Inst, FIN-00101 Helsinki, Finland

[5] Univ Parma, Univ Hosp Parma, UO Med Immunol, Lab Allergol,Dept Clin & Expt Med, I-43100 Parma, Italy

[6] Med Univ Vienna, Res Unit Aerobiol & Pollen Informat, Dept Otorhinolaryngol, Vienna, Austria

[7] Univ Florence, Interdept Ctr Bioclimatol, Florence, Italy

[8] Uludag Univ, Sci & Arts Fac, Dept Biol, Aerobiol Lab, Gorukle, Turkey

[9] Adam Mickiewicz Univ, Fac Biol, Lab Aeropalynol, Poznan, Poland

[10] Univ Worcester, Natl Pollen & Aerobiol Res Unit, Worcester, England

[11] Univ Turku, Aerobiol Unit, CERUT, Turku, Finland

[12] Allergopharma Joachim Ganzer KG, Reinbek, Germany

[13] Siauliai Univ, Dept Environm Res, Shiauliai, Lithuania

[14] RNSA, Brussieu, France

[15] Tech Univ Munich, Helmholtz Ctr Munich, ZAUM Ctr Allergy & Environm, D-80802 Munich, Germany

[16] Kuhne Fdn, CK CARE, Munich, Germany

来源：

ALLERGY | 2013年 / 68卷 / 06期

关键词：

allergy; enzyme-linked immunosorbent assay; HIALINE; model; EUROPAEA POLLEN; BIRCH POLLEN; OLE-E-1;

D O I：

10.1111/all.12144

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Pollen is routinely monitored, but it is unknown whether pollen counts represent allergen exposure. We therefore simultaneously determined olive pollen and Ole e 1 in ambient air in Cordoba, Spain, and Evora, Portugal, using Hirst-type traps for pollen and high-volume cascade impactors for allergen. Pollen from different days released 12-fold different amounts of Ole e 1 per pollen (both locations P<0.001). Average allergen release from pollen (pollen potency) was much higher in Cordoba (3.9pg Ole e 1/pollen) than in Evora (0.8pg Ole e 1/pollen, P=0.004). Indeed, yearly olive pollen counts in Cordoba were 2.4 times higher than in Evora, but Ole e 1 concentrations were 7.6 times higher. When modeling the origin of the pollen, >40% of Ole e 1 exposure in Evora was explained by high-potency pollen originating from the south of Spain. Thus, olive pollen can vary substantially in allergen release, even though they are morphologically identical.

引用

页码：809 / 812

页数：4

共 50 条

[1] THE CRYSTAL STRUCTURE OF THE MAJOR OLIVE POLLEN ALLERGEN OLE E 1
Wortmann, Judith
Hofer, Gerhard
Dorofeeva, Yulia
Focke-Tejkl, Margarete
Aschauer, Philipp
Pavkov-Keller, Tea
Valenta, Rudolf
Keller, Walter
[J]. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2019, 75 : E74 - E74
[2] Immunological characterisation of Ole e 11, a major olive pollen allergen
Salamanca, G.
Moreno, C.
Quiralte, J.
Barber, D.
Villalba, M.
Rodriguez, R.
[J]. ALLERGY, 2008, 63 : 500 - 500
[3] The major allergen of olive pollen Ole e 1 is a diagnostic marker for sensitization to Oleaceae
Palomares, Oscar
Swoboda, Ines
Villalba, Mayte
Balic, Nadia
Spitzauer, Susanne
Rodriguez, Rosalia
Valenta, Rudolf
[J]. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 2006, 141 (02) : 110 - 118
[4] Olive cultivar origin is a major cause of polymorphism for Ole e 1 pollen allergen
Hamman-Khalifa, AbdelMounim
Castro, Antonio Jesus
Jimenez-Lopez, Jose Carlos
Rodriguez-Garcia, Maria Isabel
Alche, Juan de Dios
[J]. BMC PLANT BIOLOGY, 2008, 8 (1)
[5] Olive cultivar origin is a major cause of polymorphism for Ole e 1 pollen allergen
AbdelMounim Hamman-Khalifa
Antonio Jesús Castro
José Carlos Jiménez-López
María Isabel Rodríguez-García
Juan de Dios Alché
[J]. BMC Plant Biology, 8
[6] Expression of Ole e 1, the major olive pollen allergen, during in-vitro pollen germination
M'rani-Alaoui, M
Castro, AJ
Alché, JD
Wang, W
Fernández, MC
Rodríguez-García, MI
[J]. PROCEEDINGS OF THE FOURTH INTERNATIONAL SYMPOSIUM ON OLIVE GROWING, VOLS 1 AND 2, 2002, (586): : 465 - 468
[7] The major olive pollen allergen, Ole e 1, interacts with raft-like microdomains
Lopez-Rodriguez, J. C.
Cruz, A.
Hidalgo, A.
San Segundo-Acosta, P.
Martin-Pedraza, L.
Villalba, M.
Rodriguez, R.
Perez-Gil, J.
Batanero, E.
Barderas, R.
[J]. ALLERGY, 2015, 70 : 129 - 129
[8] Validation of a monoclonal antibodybased method for measuring olive pollen major allergen, Ole e 1
Arilla, C.
Ibarrola, I.
Brena, S.
Santos, M.
Zamarreno, J.
Martinez, A.
Asturias, J. A.
[J]. ALLERGY, 2013, 68 : 201 - 201
[9] Hypoallergenic mutants of Ole e 1, the major olive pollen allergen, as candidates for allergy vaccines
Marazuela, E. G.
Rodriguez, R.
Barber, D.
Villalba, M.
Batanero, E.
[J]. CLINICAL AND EXPERIMENTAL ALLERGY, 2007, 37 (02): : 251 - 260
[10] Differential contribution of the isoforms of the major allergen of olive pollen Ole e 1 to the allergenicity of the whole molecule
Batanero, E
Barral, P
González, E
Huecas, S
Palomares, O
Barderas, R
Villalba, M
Rodríguez, R
[J]. ALLERGY, 2002, 57 : 65 - 65

← 1 2 3 4 5 →