IVUS Detection of Vasa Vasorum Blood Flow Distribution in Coronary Artery Vessel Wall

被引：13

作者：

Moritz, Regina ^{[1
]}

Eaker, Diane R. ^{[1
]}

Anderson, Jill L. ^{[1
]}

Kline, Timothy L. ^{[1
]}

Jorgensen, Steven M. ^{[1
]}

Lerman, Amir ^{[2
]}

Ritman, Erik L. ^{[1
]}

机构：

[1] Mayo Clin, Coll Med, Dept Physiol & Biomed Engn, Rochester, MN 55902 USA

[2] Mayo Clin, Coll Med, Dept Internal Med, Div Cardiovasc Dis, Rochester, MN 55902 USA

来源：

JACC-CARDIOVASCULAR IMAGING | 2012年 / 5卷 / 09期

基金：

美国国家卫生研究院;

关键词：

arterial wall; atherosclerosis; diffusion; embolization; perfusion; PERFUSION;

D O I：

10.1016/j.jcmg.2011.12.027

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There is an increased body of evidence to suggest that the vasa vasorum play a major role in the progression and complications of vulnerable plaque leading to acute coronary syndrome. We propose that detecting changes in the flow in the vascular wall by intravascular ultrasound signals can quantify the presence of vasa vasorum. The results obtained in a porcine model of atherosclerosis suggest that intravascular ultrasound-based estimates of blood flow in the arterial wall can be used in vivo in a clinical research setting to establish the density of vasa vasorum as an indicator of plaque vulnerability. (J Am Coll Cardiol Img 2012;5:935-40) (C) 2012 by the American College of Cardiology Foundation

引用

页码：935 / 940

页数：6

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