Pinacol coupling of benzaldehyde with TiCl2-amine

被引：0
|
作者：
Matsubara, S [1 ]
Hashimoto, Y [1 ]
Okano, T [1 ]
Utimoto, K [1 ]
机构：
[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Kyoto 6068501, Japan
来源：
SYNLETT | 1999年 / 09期
关键词：
titanium; pinacol; coupling; amine; asymmetric synthesis; diastereoselective synthesis;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A pinacol coupling of benzaldehyde with a homogeneous divalent titanium reagent, TiCl2-TMEDA-THF, gave the dl-hydrobenzoin with a high diastereoselectivity; by using an optically active amine instead of TMEDA, the reaction proceeded enantioselectively.
引用
收藏
页码：1411 / 1412
页数：2
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