The selective Aurora B kinase inhibitor AZD1152 inhibits in vitro growth in small cell lung cancer (SCLC) cell lines

被引：0
|
作者：
Helfrich, B. [1 ]
Garcia, M. [1 ]
Haney, J. [1 ]
Bunn, P. A., Jr. [1 ]
机构：
[1] Univ Colorado, Ctr Canc, Dept Med, Aurora, CO USA
来源：
EJC SUPPLEMENTS | 2008年 / 6卷 / 12期
关键词：
D O I：
10.1016/S1359-6349(08)72222-5
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：93 / 93
页数：1
相关论文
共 50 条
  • [31] Clinical evaluation of AZD1152, an i.v. inhibitor of Aurora B kinase, in patients with solid malignant tumors
    Boss, D. S.
    Witteveen, P. O.
    van der Sar, J.
    Lolkema, M. P.
    Voest, E. E.
    Stockman, P. K.
    Ataman, O.
    Wilson, D.
    Das, S.
    Schellens, J. H.
    ANNALS OF ONCOLOGY, 2011, 22 (02) : 431 - 437
  • [32] A PHASE I STUDY OF AZD1152, AN AURORA B KINASE INHIBITOR, IN JAPANESE PATIENTS WITH ADVANCED ACUTE MYELOID LEUKEMIA
    Miyawaki, S.
    Ando, K.
    Yokozawa, T.
    Yamauchi, T.
    Watanabe, T.
    Fujisawa, S.
    Uike, N.
    Sakura, T.
    Yagawa, K.
    Hotta, T.
    ANNALS OF ONCOLOGY, 2010, 21 : 176 - 176
  • [33] The specific Aurora kinase inhibitor AZD1152 significantly affects the growth of human leukaemic cells in an in vivo AML model
    Pearce, D.
    Odedra, R.
    Wilkinson, R.
    Bonnet, D.
    EXPERIMENTAL HEMATOLOGY, 2006, 34 (09) : 37 - 38
  • [34] AZD1152, an Aurora Kinase B Inhibitor, Sensitizes Prostate Cancer Cells Through Mitotic Arrest and Reduced DNA Damage Repair
    Mitchell, L. R.
    Kopsombut, P.
    Li, J.
    Kim, K.
    Sun, Y.
    Lu, B.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 75 (03): : S569 - S569
  • [35] Aurora kinase inhibitor AZD1152 has an additional effect of platinum on a sequential application at the human ovarian cancer cell line SKOV3
    Yaxi Ma
    Jörg Weimer
    Regina Fredrik
    Sabine Adam-Klages
    Susanne Sebens
    Amke Caliebe
    Felix Hilpert
    Christel Eckmann-Scholz
    Norbert Arnold
    Christian Schem
    Archives of Gynecology and Obstetrics, 2013, 288 : 173 - 182
  • [36] Aurora kinase inhibitor AZD1152 has an additional effect of platinum on a sequential application at the human ovarian cancer cell line SKOV3
    Ma, Yaxi
    Weimer, Joerg
    Fredrik, Regina
    Adam-Klages, Sabine
    Sebens, Susanne
    Caliebe, Amke
    Hilpert, Felix
    Eckmann-Scholz, Christel
    Arnold, Norbert
    Schem, Christian
    ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2013, 288 (01) : 173 - 182
  • [37] Effects of AZD1152, a selective Aurora B kinase inhibitor, on Burkitt's and Hodgkin's lymphomas (vol 81, pg 1106, 2011)
    Mori, Naoki
    Ishikawa, Chie
    Senba, Masachika
    Kimura, Masashi
    Okano, Yukio
    BIOCHEMICAL PHARMACOLOGY, 2011, 82 (09) : 1252 - 1252
  • [38] AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo
    Yang, Jing
    Ikezoe, Takayuki
    Nishioka, Chie
    Tasaka, Taizo
    Taniguchi, Ayuko
    Kuwayama, Yoshio
    Komatsu, Naoki
    Bandobashi, Kentaro
    Togitani, Kazuto
    Koeffler, H. Phillip
    Taguchi, Hirokuni
    Yokoyama, Akihito
    BLOOD, 2007, 110 (06) : 2034 - 2040
  • [39] AZD1152, highly potent Aurora kinase inhibitor, with selectivity for Aurora kinase B, induces pharmacodynamic effects and significant growth inhibition in human tumor xenograft models.
    Wilkinson, RW
    Odedra, R
    Heaton, SP
    Keen, N
    Wedge, SR
    Brown, E
    Crafter, C
    Foote, KM
    Mortlock, AA
    Jung, FH
    Heron, NM
    Brady, MC
    Khatri, L
    Foster, JJ
    Green, S
    CLINICAL CANCER RESEARCH, 2005, 11 (24) : 9085S - 9085S
  • [40] Determinants of Aurora kinase B inhibitor sensitivity in small cell lung cancer
    Duan, Lei
    Maki, Carl G.
    TRANSLATIONAL LUNG CANCER RESEARCH, 2024, 13 (02) : 223 - 228
12345