Photocrosslinked Poly(vinyl alcohol) Nanofibrous Scaffolds

被引：5
|
作者：
Chen, Shaohua [1 ]
Liu, Yuansen [2 ]
Dong, Qi [1 ]
Zhou, Yingshan [1 ]
Yin, Xianze [1 ]
Chen, Dongzhi [1 ]
Xu, Changan [2 ]
Xu, Weilin [1 ]
机构：
[1] Wuhan Text Univ, Minist Educ, Key Lab Green Proc & Funct Text New Text Mat, Wuhan 430073, Peoples R China
[2] State Ocean Adm, Inst Oceanog 3, Engn Res Ctr Marine Biol Resource Comprehens Util, Xiamen 361005, Peoples R China
来源：
JOURNAL OF PHOTOPOLYMER SCIENCE AND TECHNOLOGY | 2016年 / 29卷 / 06期
基金：
湖北省教育厅重点项目;
关键词：
electrospinning; poly(vinyl alcohol); photopolymerization; wound; dressing; MECHANICAL-PROPERTIES; BLEND NANOFIBERS; WOUND DRESSINGS; TISSUE; FABRICATION; MEMBRANE; DEPOSITION; MORPHOLOGY; HYDROGELS;
D O I：
10.2494/photopolymer.29.841
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Biocompatible photocrosslinked poly(vinyl alcohol) nanofibrous Scaffolds were successfully prepared by electrospinning and consequent photopolymerization. The nanofibrous membranes were subjected to detailed analysis by scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and X-ray diffraction (XRD). SEM images showed that morphology and diameter of the nanofibers were mainly affected by degree of substitute of metharyloyl group. XRD and DSC demonstrated form of a larger fraction of amorphous phase due to destroyed hydrogen bonding through methacrylation. Water stability test showed that the nanofibrous membranes improved its water stability with crosslinking degree increased. The indirect cytotoxicity assessments of the nanofibers were studied. And the result indicated the nanofibers was nontoxic to the L929 cells. This novel electrospun matrix would be used as potential wound dressing for skin regeneration.
引用
收藏
页码：841 / 847
页数：7
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