Molecular diagnostics in hematological disorders

被引：0

作者：

Mazzella, FM ^{[1
]}

Burns, JP ^{[1
]}

Alvares, CJ ^{[1
]}

Schumacher, HR ^{[1
]}

机构：

[1] Med Coll Georgia, Dept Pathol & Lab Med, Augusta, GA 30912 USA

来源：

JOURNAL OF CLINICAL LIGAND ASSAY | 2001年 / 24卷 / 03期

关键词：

molecular; leukemia; lymphoma; fluorescence in situ hybridization (FISH); cytogenetics; comparative genomic hybridization (CGH); polymerase chain reaction (PCR); fluorescence immunophenotyping and interphase; cytogenetics as a tool for investigation of neoplasms (FICTION); serial analysis of gene expression (SAGE); microarray;

D O I：

暂无

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Currently, the gold standards for the diagnosis and treatment of hematopoietic malignancies remain the morphologic features, karyotype and flow cytometric analysis. However, the time to correlate these standard-bearers with molecular diagnostic testing is upon us. Molecular biological techniques have, in fact, revolutionized the diagnosis and management of a wide variety of medical disorders, and have had a major impact on all medical disciplines, particularly hematology. Hematology already greatly relies on specialized molecular procedures for the diagnosis and management of patients. Molecular-genetic testing is anticipated to result in improved cytoreduction, as well as increased cure rates for these patients in the near future.

引用

页码：172 / 191

页数：20

共 50 条

[21] HEMATOLOGICAL DISORDERS
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