Peptide bicycles that inhibit the Grb2 SH2 domain

被引:0
|
作者
Quartararo, Justin S. [1 ]
Wu, Pianpian [1 ]
Kritzer, Joshua A. [1 ]
机构
[1] Tufts Univ, Dept Chem, Medford, MA 01450 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
119-BIOL
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Design and synthesis of conformationally constrained Grb2 SH2 domain inhibitors.
    Gao, Y
    Voigt, JH
    Kelley, J
    Yang, DJ
    Burke, TR
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 220 : U580 - U580
  • [22] Solution structure of the SH2 domain of Grb2 complexed with the Shc-derived phosphotyrosine-containing peptide
    Ogura, K
    Tsuchiya, S
    Terasawa, H
    Yuzawa, S
    Hatanaka, H
    Mandiyan, V
    Schlessinger, J
    Inagaki, F
    JOURNAL OF MOLECULAR BIOLOGY, 1999, 289 (03) : 439 - 445
  • [23] Development of binding assays for the SH2 domain of Grb7 and Grb2 using fluorescence polarization
    Luzy, Jean-Philippe
    Chen, Huixiong
    Gril, Brunilde
    Liu, Wang-Qing
    Vidal, Michel
    Perdereau, Dominique
    Burnol, Anne-Franicoise
    Garbay, Christiane
    JOURNAL OF BIOMOLECULAR SCREENING, 2008, 13 (02) : 112 - 119
  • [24] RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2
    María Jesús Lorenzo
    Gerald D Gish
    Carol Houghton
    Timothy J Stonehouse
    Tony Pawson
    Bruce AJ Ponder
    Darrin P Smith
    Oncogene, 1997, 14 : 763 - 771
  • [25] RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2
    Lorenzo, MJ
    Gish, GD
    Houghton, C
    Stonehouse, TJ
    Pawson, T
    Ponder, BAJ
    Smith, DP
    ONCOGENE, 1997, 14 (07) : 763 - 771
  • [26] Olefin metathesis in the design and synthesis of a globally constrained Grb2 SH2 domain inhibitor
    Gao, Y
    Wei, CQ
    Burke, TR
    ORGANIC LETTERS, 2001, 3 (11) : 1617 - 1620
  • [27] Monocarboxylic-based phosphotyrosyl mimetics in the design of Grb2 SH2 domain inhibitors
    Burke, TR
    Luo, J
    Yao, ZJ
    Gao, Y
    Zhao, H
    Milne, GWA
    Guo, RB
    Voigt, JH
    King, CR
    Yang, DJ
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (03) : 347 - 352
  • [28] Basic study on SH2 domain of Grb2 as a molecular probe for detection of RTK activation
    Saito, Yuriko
    Furukawa, Takako
    Arano, Yasushi
    Fujibayashi, Yasuhisa
    Saga, Tsuneo
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2010, 37 (02) : 281 - 287
  • [29] Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2
    Ettmayer, P
    France, D
    Gounarides, J
    Jarosinski, M
    Martin, MS
    Rondeau, JM
    Sabio, M
    Topiol, S
    Weidmann, B
    Zurini, M
    Bair, KW
    JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (06) : 971 - 980
  • [30] Solution structure of the Grb2 SH2 domain complexed with a high-affinity inhibitor
    Kenji Ogura
    Takanori Shiga
    Masashi Yokochi
    Satoru Yuzawa
    Terrence R. Burke
    Fuyuhiko Inagaki
    Journal of Biomolecular NMR, 2008, 42 : 197 - 207