Ce(OTf)3-catalyzed multicomponent domino cyclization-aromatization of ferrocenylacetylene, aldehydes, and amines: a straightforward synthesis of ferrocene-containing quinolines

被引：23

作者：

Chen, Shufeng ^{[1
]}

Li, Ling ^{[1
]}

Zhao, Haiying ^{[1
]}

Li, Baoguo ^{[1
]}

机构：

[1] Inner Mongolia Univ, Coll Chem & Chem Engn, Hohhot 010021, Peoples R China

来源：

TETRAHEDRON | 2013年 / 69卷 / 30期

基金：

中国国家自然科学基金;

关键词：

Aldehyde; Amine; Cerium triflate; Ferrocenylacetylene; Multicomponent reaction; Quinoline; METAL-CATALYZED REACTIONS; SUBSTITUTED; 2-ALKYLQUINOLINES; BIOORGANOMETALLIC CHEMISTRY; TANDEM REACTION; DERIVATIVES; FACILE; MODULATORS; FERROCIFEN; ALKYNES; ROUTE;

D O I：

10.1016/j.tet.2013.05.026

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A straightforward and economic method for the synthesis of ferrocene-containing quinolines by the Ce(OTf)(3)-catalyed one-pot three-component domino cyclization/aromatization reaction of ferrocenylacetylene, aldehydes, and amines under an air atmosphere was developed. A series of ferrocene substituted quinolines have been synthesized from simple and readily available starting materials in good yields. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：6223 / 6229

页数：7

共 4 条

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Kulkarni, Aditya
Torok, Bela
GREEN CHEMISTRY, 2010, 12 (05) : 875 - 878
[2] Synthesis of quinolines by a solid acid-catalyzed microwave-assisted domino cyclization-aromatization approach
De Paolis, Omar
Teixeira, Liliana
Toeroek, Bela
TETRAHEDRON LETTERS, 2009, 50 (24) : 2939 - 2942
[3] Sc(OTf)3-catalyzed three-component reactions of aldehydes, amines and allyltributylstannane in micellar systems.: Facile synthesis of homoallylic amines in water
Kobayashi, S
Busujima, T
Nagayama, S
CHEMICAL COMMUNICATIONS, 1998, (01) : 19 - 20
[4] Convenient Synthesis of Quinoline-4-carboxylate Derivatives through the Bi(OTf)3-Catalyzed Domino Cyclization/Esterification Reaction of Isatins with Enaminones in Alcohols
Zhou, Pan
Hu, Biao
Wang, Yanqin
Zhang, Qiaohe
Li, Xiang
Yan, Shengjiao
Yu, Fuchao
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2018, 2018 (33) : 4527 - 4535

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