Desmoplastic Small Round Cell Tumors in a Young Man

被引：2

作者：

Hirano, Genryu ^{[1
]}

Irie, Makoto ^{[1
]}

Nakashima, Yuta ^{[2
]}

Shakado, Satoshi ^{[1
]}

Sohda, Tetsuro ^{[1
]}

Tanaka, Toshihiro ^{[2
]}

Takamatsu, Yasushi ^{[2
]}

Aoki, Mikiko ^{[3
]}

Tamura, Kazuo ^{[2
]}

Nabeshima, Kazuki ^{[3
]}

Sakisaka, Shotaro ^{[1
]}

机构：

[1] Fukuoka Univ, Fac Med, Dept Gastroenterol & Med, Fukuoka, Japan

[2] Fukuoka Univ, Fac Med, Dept Med Oncol Hematol & Infect Dis, Fukuoka, Japan

[3] Fukuoka Univ, Fac Med, Dept Pathol, Fukuoka, Japan

来源：

INTERNAL MEDICINE | 2013年 / 52卷 / 17期

关键词：

chemotherapy; desmoplastic small round cell tumor; EWS-WT1 gene fusion transcript; reverse transcriptase polymerase chain reaction; TRANSLOCATION; 22)(P13; T(11;

D O I：

10.2169/internalmedicine.52.0431

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A previously healthy 18-year-old man was admitted to our hospital with abdominal pain in September 2010. We performed a percutaneous biopsy of multiple intrahepatic masses. A diagnosis of desmoplastic small round cell tumors was confirmed based on the presence of a polyphenotypic immunoprofile (positivity for EMA, vimentin, cytokeratin, desmin and WT1) and characteristic EWS-WT1 gene fusion. Because the mass had invaded the mesentery and the disease had disseminated to liver, the patient received palliative chemotherapy with carboplatin, paclitaxel, vincristine, doxorubicin, cyclophosphamide, ifosfamide, etoposide and irinotecan. The maximal response to the chemotherapy was a partial remission. The patient died 20 months after diagnosis.

引用

页码：1909 / 1914

页数：6

共 50 条

[21] Atypical desmoplastic small round cell tumor in a very young child
Berrebi, Dominique
Benkirane, Amal
Ferkdadji, Latifa
de Lagausie, Pascal
Delattre, Olivier
Chomette, Pascale
Schleiermacher, Gudrun
Michon, Jean
Peuchmaur, Michel
[J]. ANNALES DE PATHOLOGIE, 2007, 27 (01) : 53 - 55
[22] Management of desmoplastic small round cell
Hayes-Jordan, Andrea
LaQuaglia, Michael P.
Modak, Shakeel
[J]. SEMINARS IN PEDIATRIC SURGERY, 2016, 25 (05) : 299 - 304
[23] Desmoplastic small round cell tumor
Leuschner, I
Radig, K
Harms, D
[J]. SEMINARS IN DIAGNOSTIC PATHOLOGY, 1996, 13 (03) : 204 - 212
[24] Desmoplastic small round cell tumors with EWS-WT1 fusion transcript in children and young adults
Philippe-Chomette, Pascale
Kabbara, Nabil
Andre, Nicolas
Pierron, Gaelle
Coulomb, Aurore
Laurence, Valerie
Blay, Jean-Yves
Delattre, Olivier
Schleiermacher, Gudrun
Orbach, Daniel
[J]. PEDIATRIC BLOOD & CANCER, 2012, 58 (06) : 891 - 897
[25] Desmoplastic small round cell tumor
Drugas, GT
Boulanger, B
Korones, DN
Katzman, PJ
Koniaris, LG
[J]. PEDIATRIC BLOOD & CANCER, 2004, 42 (05) : 489 - 492
[26] Desmoplastic small round cell tumors: Multimodality treatment and new risk factors
Scheer, Monika
Vokuhl, Christian
Blank, Bernd
Hallmen, Erika
von Kalle, Thekla
Muenter, Marc
Wessalowski, Ruediger
Hartwig, Maite
Sparber-Sauer, Monika
Schlegel, Paul-Gerhardt
Kramm, Christof M.
Kontny, Udo
Spriewald, Bernd
Kegel, Thomas
Bauer, Sebastian
Kazanowska, Bernarda
Niggli, Felix
Ladenstein, Ruth
Ljungman, Gustaf
Jahnukainen, Kirsi
Fuchs, Joerg
Bielack, Stefan S.
Klingebiel, Thomas
Koscielniak, Ewa
[J]. CANCER MEDICINE, 2019, 8 (02): : 527 - 542
[27] Desmoplastic Small Round Cell Tumors With Atypical Presentations: A Report of 34 Cases
Al-Ibraheemi, Alyaa
Broehm, Cory
Tanas, Munir R.
Horvai, Andrew E.
Rubin, Brian P.
Cheah, Alison L.
Thway, Khin
Fisher, Cyril
Bahrami, Armita
Folpe, Andrew L.
Fritchie, Karen J.
[J]. INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, 2019, 27 (03) : 236 - 243
[28] Desmoplastic small round cell tumors: Prognostic indicators and results of surgical management
Roderich E. Schwarz
William L. Gerald
Brian H. Kushner
Daniel G. Coit
Murray F. Brennan
Michael P. La Quaglia
[J]. Annals of Surgical Oncology, 1998, 5 : 416 - 422
[29] POLYPHENOTYPIC SMALL ROUND-CELL TUMORS - AN IMMUNOHISTOLOGIC COMPARISON OF DESMOPLASTIC VARIANTS
SWANSON, PE
WICK, MR
GARINCHESA, P
DEHNER, LP
[J]. LABORATORY INVESTIGATION, 1994, 70 (01) : A11 - A11
[30] Desmoplastic small round cell tumors: Prognostic indicators and results of surgical management
Schwarz, RE
Gerald, WL
Kushner, BH
Coit, DG
Brennan, MF
La Quaglia, MP
[J]. ANNALS OF SURGICAL ONCOLOGY, 1998, 5 (05) : 416 - 422

← 1 2 3 4 5 →