Effect of MUC8 on Airway Inflammation: A Friend or a Foe?

被引：7
|
作者：
Cha, Hee-Jae [1 ]
Song, Kyoung Seob [2 ]
机构：
[1] Kosin Univ, Coll Med, Dept Parasitol & Genet, 34 Amnam Dong, Busan 49267, South Korea
[2] Kosin Univ, Dept Physiol, Coll Med, 34 Amnam Dong, Busan 49267, South Korea
来源：
JOURNAL OF CLINICAL MEDICINE | 2018年 / 7卷 / 02期
关键词：
MUC8; airway inflammation; inflammatory cytokines; mucus hypersecretion/overproduction; negative regulator; ACTIVATED PROTEIN-KINASE; ELEMENT-BINDING PROTEIN; EPITHELIAL-CELLS; GENE-EXPRESSION; P38; MAPK; UP-REGULATION; MUC5AC; HYPERSECRETION; ORGANIZATION; SECRETION;
D O I：
10.3390/jcm7020026
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this review, we compile identifying molecular mechanisms of MUC8 gene expression and studies characterizing the physiological functions of MUC8 in the airway and analyzing how altered MUC8 gene expression in the lung is affected by negative regulators.
引用
收藏
页数：5
相关论文
共 50 条
  • [1] ADAM8 in Asthma Friend or Foe to Airway Inflammation?
    Chen, Jun
    Jiang, Xuemei
    Duan, Yiyuan
    Long, Jiaoyue
    Bartsch, Joerg W.
    Deng, Linhong
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2013, 49 (06) : 875 - 884
  • [2] Airway inflammation in COPD - Friend or foe?
    Brusasco, Vito
    Crimi, Emanuele
    Pellegrino, Riccardo
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2007, 176 (05) : 425 - 426
  • [3] Silencing of MUC8 by siRNA increases P2Y2-induced airway inflammation
    Cha, Hee-Jae
    Jung, Min-Su
    Ahn, Do Whan
    Choi, Jang-Kyu
    Ock, Mee Sun
    Kim, Kyung Soo
    Yoon, Joo-Heon
    Song, Eun Ju
    Song, Kyoung Seob
    AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2015, 308 (06) : L495 - L502
  • [4] Inflammation: Friend and Foe
    Kjekshus, John
    EBIOMEDICINE, 2015, 2 (07): : 634 - +
  • [5] INFLAMMATION AND CANCER: FRIEND OR FOE
    Roxburgh, C. S.
    ANNALS OF THE RHEUMATIC DISEASES, 2018, 77 : 3 - 3
  • [6] Inflammation and cancer: friend or foe?
    Turizo-Smith, Andres David
    Cordoba-Hernandez, Samantha
    Mejia-Guarnizo, Lidy Vannessa
    Monroy-Camacho, Paula Stefany
    Rodriguez-Garcia, Josefa Antonia
    FRONTIERS IN PHARMACOLOGY, 2024, 15
  • [7] Inflammation: Friend or foe? Foreword
    Novak, M. John
    PHARMACOLOGICAL RESEARCH, 2011, 63 (02) : 98 - 98
  • [8] Iron and inflammation, friend or foe?
    Lasocki, Sigismond
    CAHIERS DE NUTRITION ET DE DIETETIQUE, 2012, 47 (03): : 125 - 133
  • [9] Inflammation and Nutrition: Friend or Foe?
    Stumpf, Franziska
    Keller, Bettina
    Gressies, Carla
    Schuetz, Philipp
    NUTRIENTS, 2023, 15 (05)
  • [10] Inflammation in the uterus: friend or foe?
    Chaouat, G.
    JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2012, 94 (01) : 14 - 14
12345