A saponin with anti-ulcerogenic effect from the flowers of Spartium junceum

被引:35
|
作者
Yesilada, E [1 ]
Takaishi, Y
机构
[1] Gazi Univ, Fac Pharm, TR-06330 Ankara, Turkey
[2] Univ Tokushima, Fac Pharmaceut Sci, Tokushima 770, Japan
关键词
Spartium junceum L; Fabaceae; Spartitrioside; triterpenic saponin; oleanene-type saponin;
D O I
10.1016/S0031-9422(99)00198-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A new oleanene-type saponin with potent anti-ulcerogenic activity was isolated from the flowers of Spartium junceum. The various techniques of NMR spectral analysis, viz. H-1, C-13, DEFT, C-H COSY, H-H COSY, COLOC, NOESY, HMBC, HMQC, in conjunction with EI- and FAB-mass spectrometry, revealed that the structure of the isolated saponin was 3-O-[alpha-L-rhamnopyranosyl-(1--> 2)-O-beta-D-glucopyranosyl-(1 --> 2)-beta-D-glucuronopyranosyl]-3 beta,16 beta,22 beta,24-tetrahydroxy-olean-12-ene and named as spartitrioside. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:903 / 908
页数:6
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