Access toward Fluorenone Derivatives through Solvent-Free Ruthenium Trichloride Mediated [2+2+2] Cycloadditions

被引：29
|
作者：
Ye, Fei [1 ]
Haddad, Mansour [1 ]
Michelet, Veronique [1 ]
Ratovelomanana-Vidal, Virginie [1 ]
机构：
[1] PSL Res Univ, Chim ParisTech, CNRS, Inst Rech Chim Paris, F-75005 Paris, France
来源：
ORGANIC LETTERS | 2016年 / 18卷 / 21期
关键词：
C-H ACTIVATION; PALLADIUM-CATALYZED CYCLOCARBONYLATION; FREE ORGANIC SYNTHESES; AZAFLUORENONE ALKALOIDS; SYNTHETIC APPLICATIONS; ARUNDINA-GRAMNIFOLIA; BENZOIC ANHYDRIDES; TRANSITION-METALS; HECK CYCLIZATION; ALDOXIME ETHERS;
D O I：
10.1021/acs.orglett.6b02840
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient and practical route for the preparation of highly substituted fluorenones and analogues via solvent-free ruthenium trichloride mediated [2 + 2 + 2] cycloaddition of alpha,omega-diynes and alkynes has been developed. This green chemistry approach involves a solventless and atom-economical catalytic process to generate densely functionalized fluorenones and related derivatives of high synthetic utility.
引用
收藏
页码：5612 / 5615
页数：4
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