Simple stepwise route to 1-substituted 2-amino-3-ethoxycarbonylindolizines

被引：20

作者：

Khoroshilov, Gennadiy E. ^{[1
]}

Tverdokhleb, Natalia M. ^{[1
]}

Brovarets, Vladimir S. ^{[2
]}

Babaev, Eugene V. ^{[3
]}

机构：

[1] Lugansk Taras Shevchenko Natl Univ, UA-91011 Lugansk, Ukraine

[2] Natl Acad Sci Ukraine, Inst Bioorgan Chem & Petrochem, UA-02660 Kiev, Ukraine

[3] Moscow MV Lomonosov State Univ, Dept Chem, Mosocow 119991, Russia

来源：

TETRAHEDRON | 2013年 / 69卷 / 21期

关键词：

2-Aminoindolizine; Pyrrole ring synthesis; CH-acids; 2-Chloro-Nethoxycarbonyl-methylpyridinium bromide; SALTS;

D O I：

10.1016/j.tet.2013.02.049

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Chloro-N-ethoxycarbonylmethylpyridinium bromide reacts with substituted acetonitriles in two steps; the initially formed pyridine anhydro baseses undergo further ring closure to 2-amino-3-ethoxycarbonylindolizines. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：4353 / 4357

页数：5

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