MICROWAVE-ASSISTED MULTICOMPONENT SYNTHESIS OF BENZO[f]PYRROLO[1,2-a]QUINOLINE DERIVATIVES

被引：1

作者：

Georgescu, Emilian ^{[1
]}

Georgescu, Florentina ^{[2
]}

Dumitrascu, Florea ^{[3
]}

Draghici, Constantin ^{[3
]}

Nicolescu, Alina ^{[3
,4
]}

Marinescu, Daniela ^{[1
]}

Deleanu, Calin ^{[3
,4
]}

机构：

[1] Chimcomplex Res Ctr, Str Uzinei 1, RO-240050 Ramnicu Valcea, Romania

[2] Enpro Soctech Com Srl, RO-050524 Bucharest, Romania

[3] Roumanian Acad, CD Nenitescu Ctr Organ Chem, Spl Independentei 202-B, RO-060023 Bucharest, Romania

[4] Roumanian Acad, Petru Poni Inst Macromol Chem, Aleea Grigore Ghica Voda 41-A, RO-700487 Iasi, Romania

来源：

REVUE ROUMAINE DE CHIMIE | 2020年 / 65卷 / 01期

关键词：

CYCLOADDITION REACTIONS;

D O I：

10.33224/rrch.2020.65.1.11

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We present an efficient one-pot, three component microwave-assisted synthesis of benzo[f]pyrrolo[1,2-a]quinoline derivatives starting from benzo[f]quinoline, 2-bromo-acetophenones or 2-chloro-(N-phenyl)acetamides and electron-deficient alkynes. This synthetic strategy provides a direct and easy access to a range of novel benzo[f]pyrrolo[1,2-a]quinoline derivatives. The method has the advantages of considerable shorter reaction time, reduced solvent consumption, operational simplicity and minimal impact on the environment. Nine new benzo[f]pyrrolo[1,2-a]quinoline derivatives have been synthesized with the new method and they are fully characterized.

引用

页码：97 / 102

页数：6

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