Drug Repurposing and the Medicinal Chemist

被引：58
|
作者：
Aube, Jeffrey [1 ]
机构：
[1] Univ Kansas, Dept Med Chem, Delbert M Shankel Struct Biol Ctr, Lawrence, KS 66047 USA
来源：
ACS MEDICINAL CHEMISTRY LETTERS | 2012年 / 3卷 / 06期
关键词：
OLD DRUGS; DISCOVERY;
D O I：
10.1021/ml300114c
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Drug repurposing is an approach to finding new uses for older drugs and has been gaining popularity in recent years. The role of traditional medicinal chemistry in the context of these efforts is considered.
引用
收藏
页码：442 / 444
页数：3
相关论文
共 50 条
  • [31] Synthetic information challenges for the medicinal chemist
    He, Haiying
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [32] Expanding the medicinal chemist's toolbox
    Boffey, Ray
    Manufacturing Chemist, 2021, 92 (05): : 22 - 25
  • [33] REMINISCENCES AND MUSINGS OF A CLASSICAL MEDICINAL CHEMIST
    MAY, EL
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1979, (SEP): : 34 - &
  • [34] AlphaFold for a medicinal chemist: tool or toy?
    Ivanenkov, Yan A.
    Evteev, Sergei A.
    Malyshev, Alexander S.
    Terentiev, Victor A.
    Bezrukov, Dmitry S.
    Ereshchenko, Alexey V.
    Korzhenevskaya, Anastasia A.
    Zagribelnyy, Bogdan A.
    Shegai, Petr V.
    Kaprin, Andrey D.
    RUSSIAN CHEMICAL REVIEWS, 2024, 93 (03)
  • [35] Inside the Mind of a Medicinal Chemist: The Role of Human Bias in Compound Prioritization during Drug Discovery
    Kutchukian, Peter S.
    Vasilyeva, Nadya Y.
    Xu, Jordan
    Lindvall, Mika K.
    Dillon, Michael P.
    Glick, Meir
    Coley, John D.
    Brooijmans, Natasja
    PLOS ONE, 2012, 7 (11):
  • [36] Medicinal chemistry and drug discovery: A day in the life of Mr. E. Chemist.
    Williams, TM
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1998, 216 : U350 - U350
  • [37] Sulfilimines from a Medicinal Chemist's Perspective: Physicochemical and in Vitro Parameters Relevant for Drug Discovery
    Greenwood, Nathaniel S.
    Boyer, Zachary W.
    Ellman, Jonathan A.
    Gnamm, Christian
    JOURNAL OF MEDICINAL CHEMISTRY, 2025,
  • [38] The key new techniques in the medicinal chemist's toolkit to prioritize solubility during drug design
    Sahu, Pooja
    Kumar, Rajnish
    FUTURE MEDICINAL CHEMISTRY, 2022, 14 (20) : 1421 - 1424
  • [39] Sulfoximines from a Medicinal Chemist's Perspective: Physicochemical and in vitro Parameters Relevant for Drug Discovery
    Frings, Marcus
    Bolm, Carsten
    Blum, Andreas
    Gnamm, Christian
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 126 : 225 - 245
  • [40] DRUG REPURPOSING
    Thayer, Ann M.
    CHEMICAL & ENGINEERING NEWS, 2012, 90 (40) : 15 - +
12345