Organotin (IV) derivatives of 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid (nalidixic acid): Synthesis, structural elucidation and biological activities

被引：0
|
作者：
Ahmed, Sajjad [1 ]
Bhatti, Moazzam Hussain [1 ]
Ali, Saqib [1 ]
Ahmed, Fiaz [1 ]
机构：
[1] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan
来源：
TURKISH JOURNAL OF CHEMISTRY | 2006年 / 30卷 / 02期
关键词：
organotin(IV) complexes; 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid (nalidixic acid); spectroscopic characterization; biological activity;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Organotin carboxylates of the general formulae R2SnL2 and R3SnL, where R = CH3, n-C4H9, C6H5, CH2C6H5 and L = 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid (nalidixic acid), have been prepared. These compounds were characterized by FT-IR, mass and multinuclear NMR (H-1, C-13 and Sn-119) spectroscopy. The geometry around the tin atom is compared both in solution and in solid state. These compounds were also screened for their antifungal and antibacterial activities.
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页码：193 / 202
页数：10
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