First asymmetric synthesis of (2R,3R)-3-amino-1-benzyl-2-methylpyrrolidine via a highly diastereoselective reductive alkylation

被引：45
|
作者：
Huang, PQ
Wang, SL
Zheng, H
Fei, XS
机构：
[1] Department of Chemistry, Xiamen University
来源：
TETRAHEDRON LETTERS | 1997年 / 38卷 / 02期
关键词：
D O I：
10.1016/S0040-4039(96)02301-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first asymmetric synthesis of (2R, 3R)-3-amino-1-benzyl-2-methylpyrrolidine the parent diamine of antipsychotic agent, emonapride, from (S)-malic acid was achieved via a highly diastereroselective reductive alkylation. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码：271 / 272
页数：2
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