All Things to All People

被引：23
|
作者：
Littlewood, Trevor D. [1 ]
Kreuzaler, Peter [1 ]
Evan, Gerard I. [1 ]
机构：
[1] Univ Cambridge, Dept Biochem, Cambridge CB2 1GA, England
来源：
CELL | 2012年 / 151卷 / 01期
关键词：
D O I：
10.1016/j.cell.2012.09.006
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Myc is an enigma wrapped in a mystery. Attempts to identify Myc target genes, particularly in cancer, have been fraught with dead ends and context-specific functions. Lin et al. and Nie et al. address this conundrum by showing that Myc acts to amplify the output of existing transcriptionally active genes.
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页码：11 / 13
页数：4
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