All Things to All People

被引：23

作者：

Littlewood, Trevor D. ^{[1
]}

Kreuzaler, Peter ^{[1
]}

Evan, Gerard I. ^{[1
]}

机构：

[1] Univ Cambridge, Dept Biochem, Cambridge CB2 1GA, England

来源：

CELL | 2012年 / 151卷 / 01期

关键词：

D O I：

10.1016/j.cell.2012.09.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Myc is an enigma wrapped in a mystery. Attempts to identify Myc target genes, particularly in cancer, have been fraught with dead ends and context-specific functions. Lin et al. and Nie et al. address this conundrum by showing that Myc acts to amplify the output of existing transcriptionally active genes.

引用

页码：11 / 13

页数：4

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