Microelectrode for in vivo real-time detection of NO

被引：9
|
作者：
Dalbasti, T [1 ]
Kilinc, E
机构：
[1] Univ Ege, Sch Med, Dept Neurosurg, TR-35100 Izmir, Turkey
[2] Univ Ege, Sch Pharm, Dept Analyt Chem, TR-35100 Izmir, Turkey
来源：
NITRIC OXIDE, PT E | 2005年 / 396卷
关键词：
D O I：
10.1016/S0076-6879(05)96050-3
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Nitric oxide (NO) is gaining importance with its diverse spectrum of clinic effects. However, there is still a need for an ideal sensor to monitor its concentration in tissue. An ideal sensor should not interfere with the ongoing physiological process, while making fast, reliable, and repeatable measurements. We have designed a microelectrode for electrochemical NO measurement from tissue with relatively low interference and reliable results upon calibration. Details of electrode preparation and calibration procedure are explained along with an experiment to monitor effects of photodynamic therapy.
引用
收藏
页码：584 / 592
页数：9
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