Non-alcoholic fatty liver disease in children

被引：15
|
作者：
Janczyk, Wojciech [1 ]
Socha, Piotr [1 ]
机构：
[1] Childrens Mem Hlth Inst, Dept Gastroenterol Hepatol & Eating Disorders, Warsaw, Poland
来源：
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY | 2012年 / 36卷 / 03期
关键词：
D O I：
10.1016/j.clinre.2012.03.026
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Non-alcoholic fatty liver disease is increasingly prevalent in children, together with obesity. Transaminases, tests for insulin resistance, ultrasonography and MRI are variably used as surrogates markers of steatosis. Other liver diseases, such as Wilson disease, should be excluded. A liver biopsy is performed in selected cases: young children, familial history of severe disease, inconclusive tests for other pathologies, suspected advanced fibrosis, hypertransaminasemia despite weight loss and in clinical trials. Weight reduction, and changes in lifestyle, are the front-line treatment. Drug therapy is under evaluation. (C) 2012 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：297 / 300
页数：4
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