Hypotensive effect of chemical constituents from Aloe barbadensis

被引：25
|
作者：
Saleem, R [1 ]
Faizi, S
Siddiqui, BS
Ahmed, M
Hussain, SA
Qazi, A
Dar, A
Ahmad, SI
Qazi, MH
Akhtar, S
Hasnain, SN
机构：
[1] Hamdard Univ, Dr HMI Int Pharmacol & Herbal Sci, Karachi 74600, Pakistan
[2] Univ Karachi, HEJ Res Inst Chem, Karachi 32, Pakistan
[3] Univ Karachi, Dept Biochem, Karachi 32, Pakistan
来源：
PLANTA MEDICA | 2001年 / 67卷 / 08期
关键词：
D O I：
10.1055/s-2001-18348
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Hypotensive effects of aloeemodin, aloin A, elgonica dimer A and bisbenzopyran from Aloe barbodensis have been studied. Aloeemodin has emerged as a potent hypotensive agent in current pharmacological investigations and caused 26%, 52%, and 79% falls in mean arterial blood pressure at the corresponding doses of 0.5, 1, and 3 mg/kg in rats. The paper also describes the absolute configuration of elgonica dimer A (1).
引用
收藏
页码：757 / 760
页数：4
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