Biochemical Markers of Bone Turnover in Rheumatoid Arthritis Patients Treated with Glucocorticoids

被引：0
|
作者：
Macovei, Luana Andreea [1 ]
Burlui, Alexandra [1 ]
Rezus, Elena [2 ]
机构：
[1] Grigore T Popa Univ Med & Pharm Iasi, Dept Rheumatol Rehabil Phys Med & Balneol, 16 Univ Str, Iasi 700115, Romania
[2] Clin Rehabil Hosp Iasi, Rheumatol Clin 1, 14 Pantelimon Halipa, Iasi 700656, Romania
来源：
REVISTA DE CHIMIE | 2019年 / 70卷 / 02期
关键词：
glucocorticoids; osteocalcin; deoxypyridinoline; BIOMARKERS; INTOXICATION; METABOLISM;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Osteocalcin and deoxypyridinoline levels were measured in 55 RA patients during and after glucocorticoid therapy with prednisone, methylprednisolone and cortisone. A decrease of 27% of the bone resorption marker deoxypyridinoline (from 10.13 to 7.4) and an increase of 23% of the bone formation marker osteocalcin (from 16.3 to 20.1) were also clinically confirmed by the presence of osteoporosis in 74% of patients receiving corticosteroid treatment as compared with only 31% in the control group.
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页码：623 / 626
页数：4
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