Endocrine Diseases in Animals

被引：17
|
作者：
Kooistra, H. S. [1 ]
Galac, S. [1 ]
Buijtels, J. J. C. W. M. [1 ]
Meij, B. P. [1 ]
机构：
[1] Univ Utrecht, Fac Vet Med, Dept Clin Sci Compan Anim, NL-3584 CM Utrecht, Netherlands
来源：
HORMONE RESEARCH | 2009年 / 71卷
关键词：
Dog; Cat; Animal models; Veterinary endocrinology; GROWTH-HORMONE; MAMMARY-GLAND; DIABETES-MELLITUS; DOG; GENE; HYPERADRENOCORTICISM; EXPRESSION; SECRETION; ADENOMA; CATS;
D O I：
10.1159/000178059
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background: Several endocrine disorders that affect humans also occur as endocrinopathies in companion animals. Spontaneous endocrine disorders in animals may provide valuable information for their counterparts in human endocrinology. For example, the discovery of progesterone-induced growth hormone production in the mammary gland of dogs may have important consequences for understanding the pathogenesis of breast cancer in women. In addition, the majority of diabetic cats have a type of diabetes mellitus that closely resembles type 2 diabetes mellitus in humans and therefore may serve as an animal model for this disease in humans. This review describes several endocrine diseases in companion animals that are quite similar to those in humans and emphasizes their usefulness as spontaneous animal models for human endocrine disorders. Copyright (C) 2009 S. Karger AG, Basel
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页码：144 / 147
页数：4
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