IMGN529 is an anti-CD37-maytansinoid conjugate with potent in vitro and in vivo activity against NHL and CLL cell lines

被引:0
|
作者
Mayo, Michele F. [1 ]
Li, Min [1 ]
Yi, Yong [1 ]
Xu, Shanqin [1 ]
Lai, Katharine C. [1 ]
Erickson, Hans K. [1 ]
Deckert, Jutta [1 ]
Park, Peter U. [1 ]
Lutz, Robert J. [1 ]
Pinkas, Jan [1 ]
机构
[1] ImmunoGen Inc, Waltham, MA USA
关键词
D O I
10.1158/1538-7445.AM2011-4581
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
4581
引用
收藏
页数:2
相关论文
共 43 条
  • [41] The novel ICAM-1/CD54 antibody MSH-TP15, identified by a cell-based phage display screening approach, has potent anti-myeloma activity in vitro and in vivo
    Klausz, K.
    Burger, R.
    Kellner, C.
    Peipp, M.
    Gramatzki, M.
    ONCOLOGY RESEARCH AND TREATMENT, 2014, 37 : 201 - 201
  • [42] Anti-CD20-interferon-alpha fusion protein has superior in vivo activity against human B-cell lymphomas compared to rituximab and enhanced complement-dependent cytotoxicity in vitro
    Yamada, Reiko E.
    Steward, Kristopher K.
    Ngarmchamnanrith, Gataree
    Trinh, Ryan K.
    Khare, Sanjay
    Sachdev, Raj
    Grewal, Iqbal S.
    Morrison, Sherie L.
    Timmerman, John
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [43] Ofatumumab, a Fully Human Monoclonal Antibody Targeting CD20, Demonstrates Activity Against and Potentiates the Anti-Tumor Activity of Chemotherapy Agents In Rituximab-Sensitive Cell Lines (RSCL), Rituximab-Resistant Cell Lines (RRCL), Lymphoma Xenografts, and Primary Tumor Cells Derived From Patients with B-Cell Non-Hodgkin Lymphoma (NHL)
    Barth, Matthew
    Hernandez-Ilizaliturri, Francisco J.
    Mavis, Cory
    Tsai, Ping-Chiao
    Gibbs, John
    Deeb, George
    Czuczman, Myron S.
    BLOOD, 2010, 116 (21) : 1598 - 1598