Photoacoustic guided ultrasound wavefront shaping for targeted acousto-optic imaging

被引：5
|
作者：
Staley, Jacob [1 ]
Hondebrink, Erwin [1 ]
Peterson, Wilma [1 ]
Steenbergen, Wiendelt [1 ]
机构：
[1] Univ Twente, MIRA Inst Biomed Technol & Tech Med, Biomed Photon Imaging Grp, NL-7500 AE Enschede, Netherlands
来源：
OPTICS EXPRESS | 2013年 / 21卷 / 25期
关键词：
INVIVO MEASUREMENTS; BASIC PRINCIPLES; BEAM DISTORTION; GOLD NANORODS; TIME-REVERSAL; BREAST; TOMOGRAPHY; ABERRATION; VELOCITY; SIGNALS;
D O I：
10.1364/OE.21.030553
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
To overcome speed of sound aberrations that negatively impact the acoustic focus in acousto-optic imaging, received photoacoustic signals are used to guide the formation of ultrasound wavefronts to compensate for acoustic inhomogeneities. Photoacoustic point sources composed of gold and superparamagnetic iron oxide nanoparticles are used to generate acoustic waves that acoustically probe the medium as they propagate to the detector. By utilizing cross-correlation techniques with the received photoacoustic signal, transmitted ultrasound wavefronts compensate for the aberration, allowing for optimized and configurable ultrasound transmission to targeted locations. It is demonstrated that utilizing a portable commercially available ultrasound system using customized software, photoacoustic guided ultrasound wavefront shaping for targeted acousto-optic imaging is robust in the presence of large, highly attenuating acoustic aberration. (C) 2013 Optical Society of America
引用
收藏
页码：30553 / 30562
页数：10
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