Association of serum uric acid level with ischemic stroke, stroke subtypes and clinical outcome

被引：0

作者：

Koppula, Rajeshwar ^{[1
,2
,3
]}

Kaul, Subash ^{[4
]}

Rao, A. Venkateswar ^{[1
,2
]}

Jyothy, A. ^{[1
,2
]}

Munshi, Anjana ^{[1
,2
]}

机构：

[1] Osmania Univ, Inst Genet, Hyderabad 500007, Andhra Pradesh, India

[2] Osmania Univ, Hosp Genet Dis, Hyderabad 500007, Andhra Pradesh, India

[3] Dr NTR Univ Hlth Sci, Vijayawada, Andhra Pradesh, India

[4] Nizams Inst Med Sci, Hyderabad, Andhra Pradesh, India

来源：

NEUROLOGY ASIA | 2013年 / 18卷 / 04期

关键词：

PROSPECTIVE COHORT; RISK-FACTOR; ATHEROSCLEROSIS; NEUROPROTECTION; HYPERURICEMIA; ANTIOXIDANT; PREDICTOR; DISEASE; EVENTS;

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background and Objective: Uric acid is a neuroprotective agent. However, its relationship with ischaemic stroke remains controversial. We analyzed the association between serum uric acid and ischemic stroke and clinical outcome. Methods: The study subject consisted of 550 ischemic stroke patients from the Nizam's Institute of Health Sciences, Hyderabad, India with 550 matched healthy controls. Serum uric acid levels were estimated, and follow-up interviews conducted with patients. Results: There was a significant association of elevated levels of serum uric acid with stroke and its subtypes except lacunar stroke. Patients with high serum uric acid levels had a significant increased risk of poor outcome. Conclusion: Serum uric acid level is associated with ischemic stroke, and is an independent prognostic factor of poor outcome.

引用

页码：349 / 354

页数：6

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