Syntheses of New Carbanucleosides by Pericyclic Reactions

被引:17
|
作者
Scagnelli, Luca [1 ]
Memeo, Misal Giuseppe [1 ]
Carosso, Serena [1 ]
Bovio, Bruna [1 ]
Quadrelli, Paolo [1 ]
机构
[1] Univ Pavia, Dept Chem, I-27100 Pavia, Italy
关键词
Antiviral agents; Carbanucleosides; Ene reaction; Cycloaddition; Nitrosocarbonyls; Nitrile oxides; CARBOCYCLIC NUCLEOSIDE ANALOGS; DIELS-ALDER REACTION; NITRILE OXIDES; MILD OXIDATION; ENE REACTIONS; BIOLOGICAL EVALUATION; ACYLNITROSO COMPOUNDS; HYDROXAMIC ACIDS; CONVENIENT ENTRY; 1ST SYNTHESIS;
D O I
10.1002/ejoc.201300202
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of heterobase-functionalized cyclopentene derivatives as valuable substrate for the introduction of suitable substituents through pericyclic reactions is reported. The structures of ene and 1,3-dipolar adducts are discussed, and the primary antiviral activities of some adenine derivatives are reported.
引用
收藏
页码:3835 / 3846
页数:12
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