Visual losses in early-onset and late-onset Parkinson's disease

被引：5

作者：

Feitosa-Santana, Claudia ^{[1
,2
,3
]}

Costa, Marcelo Fernandes ^{[1
,2
]}

Ferraz, Henrique Ballalai ^{[4
]}

Andrade, Luiz Augusto F. ^{[5
]}

Moura, Ana Laura ^{[6
,7
]}

Amaro Jr, Edson ^{[5
]}

Hamer, Russell D. ^{[8
]}

Ventura, Dora Fix ^{[1
,2
]}

机构：

[1] Univ Sao Paulo, Nucleo Neurociencias & Comportamento, Sao Paulo, Brazil

[2] Univ Sao Paulo, Inst Psicol, Dept Psicol Expt, Sao Paulo, Brazil

[3] Neurociencia Desenvolvimento Humano, Sao Paulo, Brazil

[4] Univ Fed Sao Paulo, Escola Paulista Med, Dept Neurol, Sao Paulo, Brazil

[5] Hosp Israelita Albert Einstein, Sao Paulo, Brazil

[6] ABC, Disciplina Oftalmol, Fac Med, Santo Andre, SP, Brazil

[7] Univ Fed Sao Paulo, Dept Oftalmol, Escola Paulista Med, Sao Paulo, Brazil

[8] Florida Atlantic Univ, Dept Psychol, Boca Raton, FL 33431 USA

来源：

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION | 2020年 / 37卷 / 05期

基金：

巴西圣保罗研究基金会;

关键词：

CONTRAST SENSITIVITY; COLOR DISCRIMINATION; SPATIAL-FREQUENCY; VISION; IMPAIRMENT; DYSFUNCTION; AMANTADINE; AGE;

D O I：

10.1364/JOSAA.382042

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Patients with Parkinson's disease (PD) manifest visual losses. However, it is not known whether these losses are equivalent in both early-onset (EOPD) and late-onset (LOPD) patients. We evaluated contrast sensitivity and color vision in EOPD and LOPD patients and in age-matched controls. Losses occurred in both patient groups but were more pronounced in EOPD, consistent with the notion that non-motor symptoms are affected by age of symptom onset. More studies of visual function in EOPD and LOPD patients are needed to understand how aging is related to the pathophysiology of non-motor PD symptomatology. This would permit earlier diagnosis and, perhaps, better management of the disease. (C) 2020 Optical Society of America

引用

页码：A285 / A293

页数：9

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