A new phenolic glycoside from Spiraea prunifolia var. simpliciflora twigs

被引：16
|
作者：
Jang, Sung Wan [1 ]
Suh, Won Se [1 ]
Kim, Chung Sub [1 ]
Kim, Ki Hyun [1 ]
Lee, Kang Ro [1 ]
机构：
[1] Sungkyunkwan Univ, Sch Pharm, Nat Prod Lab, Suwon 440746, South Korea
来源：
ARCHIVES OF PHARMACAL RESEARCH | 2015年 / 38卷 / 11期
基金：
新加坡国家研究基金会;
关键词：
Spiraea prunifolia var. simpliciflora; Phenolic glycoside; Cytotoxicity; LIGNAN GLYCOSIDE; PRUNIOSIDE-A; CONSTITUENTS; CAFFEOYL; DERIVATIVES; LEAVES;
D O I：
10.1007/s12272-015-0610-y
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The phytochemical investigation of the methanol extract from the twigs of Spiraea prunifolia var. simpliciflora (Rosaceae) using column chromatography led to the isolation of a new phenol glycoside, 1-O-(E)-caffeoyl-2-O-p-(E)-coumaroyl-beta-d-glucopyranose (1), together with 16 known phenolic compounds (2-17). The structure of this new compound was elucidated by analysis of spectroscopic data including 1D, 2D nuclear magnetic resonance and HR-FAB-MS data. The isolated compounds were tested for cytotoxicity against four human tumor cell lines in vitro using the sulforhodamine B bioassay.
引用
收藏
页码：1943 / 1951
页数：9
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