Tetraalkylammonium bromate (TAAB) catalyzed cyclodehydration: A facile synthesis of 2,3-dihydro-1H-1,5-benzodiazepine in aqueous methanol

被引：0
|
作者：
Das, Pranab Jyod [1 ]
Sarkar, Sudeshna [1 ]
机构：
[1] Gauhati Univ, Dept Chem, Gauhati 781014, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2015年 / 54卷 / 09期
关键词：
1,5-Benzodiazepines; tetraalkylammonium bromate; o-phenylenediamines; ketones; SOLVENT-FREE CONDITIONS; ONE-POT SYNTHESIS; 1,5-BENZODIAZEPINE DERIVATIVES; EFFICIENT SYNTHESIS; PROMOTED SYNTHESIS; MICROWAVE IRRADIATION; RECYCLABLE CATALYST; O-PHENYLENEDIAMINE; ACID; 1,5-BENZOTHIAZEPINES;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and convenient method is reported for the synthesis of 2,3-dihydro-1H-1,5-benzodiazepine from o-phenylene-diamine and ketones in aqueous methanol using IL, tetraalkylammonium bromate, as the cyclodehydration catalyst. The synthetic protocol is simple and reaction accomplished at ambient temperature. Yields are good and work up easy.
引用
收藏
页码：1123 / 1127
页数：5
相关论文
共 50 条
  • [21] Derivatives of 2,3-dihydro-1H-1,5-benzodiazepine from o-nitroanilines and chalcones induced by low-valent titanium
    Ma, YM
    Zhang, YM
    SYNTHETIC COMMUNICATIONS, 2002, 32 (02) : 165 - 169
  • [22] RECYCLIZATION OF 2,3-DIHYDRO-2,3-PYRROLEDIONE WITH THE FORMATION OF 1,5-BENZODIAZEPINE
    MASLIVETS, AN
    SMIRNOVA, LI
    ANDREICHIKOV, YS
    ZHURNAL ORGANICHESKOI KHIMII, 1988, 24 (07): : 1565 - 1566
  • [23] A facile synthesis of 3,4-dihydro-2-pyronyl-1,5-benzodiazepine derivatives
    Prakash, O
    Kumar, A
    Sadana, A
    Singh, SP
    SYNTHETIC COMMUNICATIONS, 2002, 32 (17) : 2663 - 2667
  • [24] SYNTHESIS AND PHARMACOLOGICAL STUDY OF 2,3-DIHYDRO-1H-1,5-BENZODIAZEPINONES-2
    STOLYARCHUK, AA
    FURMAN, YN
    PIKALOV, VL
    SOLOMKO, ZF
    TKACHENKO, VS
    KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1975, 9 (08): : 19 - 21
  • [25] Synthesis of 4-pyridyl-2,3-dihydro-1H-1,5-benzodiazepinones-2
    Bozhanov, VI
    Ivonin, SP
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2002, (09): : 1255 - 1260
  • [26] CHED 472-Synthesis of 2,3-dihydro-1H-1,5-benzodiazepines
    Conklin, Adrienne
    Yamaguchi, Kenneth
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 235
  • [27] Catalytic synthesis of 2,3-dihydro-1H-1,5-benzodiazepines by ferric perchlorate
    Heravi, Majid M.
    Zadsirjan, Vahideh
    Behbahani, Farahnaz K.
    Oskooie, Hossien A.
    JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2006, 259 (1-2) : 201 - 204
  • [28] SYNTHESIS AND MASS-SPECTRA OF 2,3-DIHYDRO-1H-1,5-BENZODIAZEPINETHIONES-2
    SOLOMKO, ZF
    SHARBATYAN, PA
    GAPONOV, AA
    AVRAMENKO, VI
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1990, (03): : 396 - 400
  • [29] Synthesis of 2, 2, 4-trimethyl-2, 3-dihydro-1H-1, 5-benzodiazepine under ultrasound irradiation
    Liu, Bo
    Lu, Wei-Zhong
    Zhang, Xue-Li
    Gao, Yuan
    Huang, Shao-Shuo
    Shenzhen Daxue Xuebao (Ligong Ban)/Journal of Shenzhen University Science and Engineering, 2008, 25 (03): : 328 - 330
  • [30] INTERACTION OF 2,3-DIHYDRO-1H-1,5-BENZODIAZEPINONE-2 WITH EPICHLORHYDRINE
    Gaponov, Oleksandr O.
    Tarabara, Igor M.
    BULLETIN OF DNIPROPETROVSK UNIVERSITY-SERIES CHEMISTRY, 2014, 22 (01): : 67 - 70
12345