SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates

被引：427
|
作者：
Poland, Gregory A. [1 ,2 ]
Ovsyannikova, Inna G. [1 ,2 ]
Kennedy, Richard B. [1 ,2 ]
机构：
[1] Mayo Clin, Mayo Clin Vaccine Res Grp, Rochester, MN USA
[2] Mayo Clin, Div Gen Internal Med, Rochester, MN USA
来源：
LANCET | 2020年 / 396卷 / 10262期
关键词：
ANTIBODY-DEPENDENT ENHANCEMENT; COVID-19; INFECTION; DISEASE; CELLS;
D O I：
10.1016/S0140-6736(20)32137-1
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Understanding immune responses to severe acute respiratory syndrome coronavirus 2 is crucial to understanding disease pathogenesis and the usefulness of bridge therapies, such as hyperimmune globulin and convalescent human plasma, and to developing vaccines, antivirals, and monoclonal antibodies. A mere 11 months ago, the canvas we call COVID-19 was blank. Scientists around the world have worked collaboratively to fill in this blank canvas. In this Review, we discuss what is currently known about human humoral and cellular immune responses to severe acute respiratory syndrome coronavirus 2 and relate this knowledge to the COVID-19 vaccines currently in phase 3 clinical trials.
引用
收藏
页码：1595 / 1606
页数：12
相关论文
共 50 条
  • [41] SARS-CoV-2 Immunity: Review of Immune Response to Infection and Vaccination
    Ahmad, Rahnuma
    BANGLADESH JOURNAL OF MEDICAL SCIENCE, 2021, 20 : S32 - S40
  • [42] AYUSH Preparations as Immunity Booster in the Management of SARS-CoV-2: A Review
    Prajapati, Suneel
    Sharma, Mahima
    Kumar, Arun
    Tripathi, Ashish
    Kumar, G. V. Narasimha
    Singh, Shilpi
    Singh, Monika
    Verma, Digvijay
    Gupta, Pankaj
    CURRENT TRADITIONAL MEDICINE, 2021, 7 (04) : 524 - 530
  • [43] Evaluation of Waning of SARS-CoV-2 Vaccine-Induced Immunity: A Systematic Review and Meta-analysis
    Menegale, Francesco
    Manica, Mattia
    Zardini, Agnese
    Guzzetta, Giorgio
    Marziano, Valentina
    d'Andrea, Valeria
    Trentini, Filippo
    Ajelli, Marco
    Poletti, Piero
    Merler, Stefano
    JAMA NETWORK OPEN, 2023, 6 (05) : E2310650
  • [44] Adaptive immunity against SARS-CoV-2
    Combadiere, Behazine
    M S-MEDECINE SCIENCES, 2020, 36 (10): : 908 - 913
  • [45] Evolution of antibody immunity to SARS-CoV-2
    Christian Gaebler
    Zijun Wang
    Julio C. C. Lorenzi
    Frauke Muecksch
    Shlomo Finkin
    Minami Tokuyama
    Alice Cho
    Mila Jankovic
    Dennis Schaefer-Babajew
    Thiago Y. Oliveira
    Melissa Cipolla
    Charlotte Viant
    Christopher O. Barnes
    Yaron Bram
    Gaëlle Breton
    Thomas Hägglöf
    Pilar Mendoza
    Arlene Hurley
    Martina Turroja
    Kristie Gordon
    Katrina G. Millard
    Victor Ramos
    Fabian Schmidt
    Yiska Weisblum
    Divya Jha
    Michael Tankelevich
    Gustavo Martinez-Delgado
    Jim Yee
    Roshni Patel
    Juan Dizon
    Cecille Unson-O’Brien
    Irina Shimeliovich
    Davide F. Robbiani
    Zhen Zhao
    Anna Gazumyan
    Robert E. Schwartz
    Theodora Hatziioannou
    Pamela J. Bjorkman
    Saurabh Mehandru
    Paul D. Bieniasz
    Marina Caskey
    Michel C. Nussenzweig
    Nature, 2021, 591 : 639 - 644
  • [46] Partial immunity and SARS-CoV-2 mutations
    Hanage, William P.
    Russell, Colin A.
    SCIENCE, 2021, 372 (6540) : 354 - 354
  • [47] Immunity after SARS-CoV-2 infections
    Jagannathan, Prasanna
    Wang, Taia T.
    NATURE IMMUNOLOGY, 2021, 22 (05) : 539 - 540
  • [48] Toward superhuman SARS-CoV-2 immunity?
    Dennis R. Burton
    Eric J. Topol
    Nature Medicine, 2021, 27 : 5 - 6
  • [49] SARS-CoV-2 immunity in animal models
    Chen, Zhao
    Yuan, Yaochang
    Hu, Qingtao
    Zhu, Airu
    Chen, Fenghua
    Li, Shu
    Guan, Xin
    Lv, Chao
    Tang, Tian
    He, Yiyun
    Cheng, Jinling
    Zheng, Jie
    Hu, Xiaoyu
    Zhao, Jingxian
    Zhao, Jincun
    Sun, Jing
    CELLULAR & MOLECULAR IMMUNOLOGY, 2024, 21 (02) : 119 - 133
  • [50] Evolution of antibody immunity to SARS-CoV-2
    Gaebler, Christian
    Wang, Zijun
    Lorenzi, Julio C. C.
    Muecksch, Frauke
    Finkin, Shlomo
    Tokuyama, Minami
    Cho, Alice
    Jankovic, Mila
    Schaefer-Babajew, Dennis
    Oliveira, Thiago Y.
    Cipolla, Melissa
    Viant, Charlotte
    Barnes, Christopher O.
    Bram, Yaron
    Breton, Gaelle
    Hagglof, Thomas
    Mendoza, Pilar
    Hurley, Arlene
    Turroja, Martina
    Gordon, Kristie
    Millard, Katrina G.
    Ramos, Victor
    Schmidt, Fabian
    Weisblum, Yiska
    Jha, Divya
    Tankelevich, Michael
    Martinez-Delgado, Gustavo
    Yee, Jim
    Patel, Roshni
    Dizon, Juan
    Unson-O'Brien, Cecille
    Shimeliovich, Irina
    Robbiani, Davide F.
    Zhao, Zhen
    Gazumyan, Anna
    Schwartz, Robert E.
    Hatziioannou, Theodora
    Bjorkman, Pamela J.
    Mehandru, Saurabh
    Bieniasz, Paul D.
    Caskey, Marina
    Nussenzweig, Michel C.
    NATURE, 2021, 591 (7851) : 639 - +
12345