Toxoplasma gondii infection of human plasmacytoid dendritic cells inactivates TLR7 and-9 mediated induction of IFN-α and TNF-α in response to HIV and HSV

被引:0
|
作者
Pierog, Piotr [1 ]
Zhao, Yanlin [1 ]
Singh, Sukhwinder [1 ]
Yap, George [1 ]
Fitzgerald-Bocarsly, Patricia [1 ]
机构
[1] Univ Med & Dent New Jersey, New Jersey Med Sch, Newark, NJ 07103 USA
来源
JOURNAL OF IMMUNOLOGY | 2011年 / 186卷
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
56.26
引用
收藏
页数:1
相关论文
共 50 条
  • [21] TLR7 and CD28 regulate plasmacytoid dendritic cell IFN-I induction and silencing during chronic viral infection
    Macal, Monica
    Hurtado, Miguel Tam
    Chang, Aaron
    Hesser, Charles
    Zuniga, Elina
    JOURNAL OF IMMUNOLOGY, 2014, 192
  • [22] Up-Regulation of TLR7-Mediated IFN-α Production by Plasmacytoid Dendritic Cells in Patients With Systemic Lupus Erythematosus
    Sakata, Kei
    Nakayamada, Shingo
    Miyazaki, Yusuke
    Kubo, Satoshi
    Ishii, Akina
    Nakano, Kazuhisa
    Tanaka, Yoshiya
    FRONTIERS IN IMMUNOLOGY, 2018, 9
  • [23] IgE suppresses TLR-9 mediated IFN-α production from human blood dendritic cells
    Tversky, J. R.
    Bieneman, A. P.
    Chichester, K. L.
    Schroeder, J. T.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2008, 121 (02) : S12 - S12
  • [24] TLR7 and-9 activation of human plasmacytoid dendritic cells enhance endocytosis and processing of membrane material from a Her2/neu positive breast cancer cells
    Pierog, Piotr
    Singh, Sukhwinder
    Fitzgerald-Bocarsly, Patricia
    JOURNAL OF IMMUNOLOGY, 2012, 188
  • [25] Human plasmacytoid dendritic cells sequentially up-regulate and co-express functional receptors and IFN-α in response to HIV and HSV stimulation.
    Awoyomi, Temitayo
    Fitzgerald-Bocarsly, Patricia
    JOURNAL OF IMMUNOLOGY, 2011, 186
  • [26] Natural and synthetic TLR7 ligands inhibit CpG-A- and CpG-C-ODN-induced IFN-α production by plasmacytoid dendritic cells
    Hackstein, Holger
    Berghoefer, Beate
    Bein, Gregor
    CLINICAL IMMUNOLOGY, 2007, 123 : S155 - S155
  • [27] Complement Component 3 Regulates IFN-α Production by Plasmacytoid Dendritic Cells following TLR7 Activation by a Plant Virus-like Nanoparticle
    Lebel, Marie-Eve
    Langlois, Marie-Pierre
    Daudelin, Jean-Francois
    Tarrab, Esther
    Savard, Pierre
    Leclerc, Denis
    Lamarre, Alain
    JOURNAL OF IMMUNOLOGY, 2017, 198 (01): : 292 - 299
  • [28] IFN-β Therapy Regulates TLR7-Mediated Response in Plasmacytoid Dendritic Cells of Multiple Sclerosis Patients Influencing an Anti-Inflammatory Status
    Severa, Martina
    Rizzo, Fabiana
    Giacomini, Elena
    Annibali, Viviana
    Gafa, Valerie
    Romano, Silvia
    Buscarinu, Maria Chiara
    Fornasiero, Arianna
    Salvetti, Marco
    Coccia, Eliana Marina
    JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 2015, 35 (09): : 668 - 681
  • [29] Monocyte-Mediated Inhibition of TLR9-Dependent IFN-α Induction in Plasmacytoid Dendritic Cells Questions Bacterial DNA as the Active Ingredient of Bacterial Lysates
    Poth, Jens M.
    Coch, Christoph
    Busch, Nicolas
    Boehm, Olaf
    Schlee, Martin
    Janke, Markus
    Zillinger, Thomas
    Schildgen, Oliver
    Barchet, Winfried
    Hartmann, Gunther
    JOURNAL OF IMMUNOLOGY, 2010, 185 (12): : 7367 - 7373
  • [30] Human Plasmacytoid Dendritic Cells Support Th17 Cell Effector Function in Response to TLR7 Ligation
    Yu, Chun-Feng
    Peng, Wen-Ming
    Oldenburg, Johannes
    Hoeh, Jochen
    Bieber, Thomas
    Limmer, Andreas
    Hartmann, Gunther
    Barchet, Winfried
    Eis-Huebinger, Anna Maria
    Novak, Natalija
    JOURNAL OF IMMUNOLOGY, 2010, 184 (03): : 1159 - 1167