Heart Failure Clinical Problem and Management Issues

被引：3

作者：

Nicklas, John M. ^{[1
]}

Bleske, Barry E. ^{[2
]}

Van Harrison, Richard ^{[3
]}

Hogikyan, Robert V. ^{[4
]}

Kwok, Yeong ^{[5
]}

Chavey, William E. ^{[6
,7
]}

机构：

[1] Univ Michigan, Dept Internal Med, Div Cardiovasc Med, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Coll Pharm, Dept Clin & Social Adm Serv, Ann Arbor, MI 48109 USA

[3] Univ Michigan, Dept Med Educ, Ann Arbor, MI 48109 USA

[4] Univ Michigan, Dept Internal Med, Div Geriatr & Palliat Med, Ann Arbor, MI 48105 USA

[5] Univ Michigan, Dept Internal Med, Div Gen Med, Ann Arbor, MI 48109 USA

[6] Univ Michigan, Sch Med, Dept Family Med, Ann Arbor, MI 48109 USA

[7] Univ Michigan, Sch Med, Dept Emergency Med, Ann Arbor, MI 48109 USA

来源：

PRIMARY CARE | 2013年 / 40卷 / 01期

关键词：

Heart failure; Cardiomyopathy; Angiotensin converting enzyme inhibitor; Beta blocker; Aldosterone antagonist; Implantable cardiodefibrillator; Biventricular pacemaker; LEFT-VENTRICULAR DYSFUNCTION; CARDIAC-RESYNCHRONIZATION THERAPY; CONVERTING-ENZYME-INHIBITORS; IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; MODERATE ALCOHOL-CONSUMPTION; HIGH-RISK; RANDOMIZED-TRIAL; SYSTOLIC FUNCTION; VENTILATORY EFFICIENCY;

D O I：

10.1016/j.pop.2012.11.010

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Heart failure (HF) often presents as dyspnea either with exertion and/or recumbency. Patients also experience dependent swelling and fatigue. Measurement of the left ventricular ejection fraction (LVEF) identifies HF patients who may respond to pharmacologic therapy and/or electrophysiologic device implantation. Angiotension converting enzyme inhibitors, beta blockers, and aldosterone inhibitors can significantly lower the mortality and morbidity of HF in patients with an LVEF less than 35%. Cardiac defibrillators and biventricular pacemakers can also improve outcomes in selected patients with a decreased LVEF. The authors provide a guide for therapeutic decisions based on the inclusion criteria of the major clinical trials.

引用

页码：17 / +

页数：27

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