Future health implications of prenatal and early-life vitamin D status

被引：74

作者：

Lucas, Robyn M. ^{[1
]}

Ponsonby, Anne-Louise ^{[2
]}

Pasco, Julie A. ^{[3
]}

Morley, Ruth ^{[2
,4
]}

机构：

[1] Australian Natl Univ, Natl Ctr Epidemiol & Populat Hlth, Canberra, ACT 0200, Australia

[2] Murdoch Childrens Res Inst, Melbourne, Vic, Australia

[3] Univ Melbourne, Dept Clin & Biomed Sci Barwon Hlth, Epidemiol & Biostat Unit, Geelong, Vic, Australia

[4] Univ Melbourne, Dept Paediat, Parkville, Vic 3052, Australia

来源：

NUTRITION REVIEWS | 2008年 / 66卷 / 12期

关键词：

chronic disease; fetus; ultraviolet radiation; vitamin D;

D O I：

10.1111/j.1753-4887.2008.00126.x

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Current or recent low vitamin D status (or proxy measures such as dietary intake or ambient ultraviolet radiation) is linked to several chronic diseases, including osteoporosis, cancers, and cardiovascular and autoimmune diseases. Low prenatal vitamin D status may also increase susceptibility to such diseases in later life via specific target organ effects and/or through changes to the developing immune system. Maternal vitamin D supplementation during pregnancy could be an important public health measure to decrease risk of a range of chronic diseases, but further research is required to clarify beneficial and adverse effects of high prenatal vitamin D.

引用

页码：710 / 720

页数：11

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