Clinical Research and Development of Tuberculosis Diagnostics: Moving From Silos to Synergy

被引：25

作者：

Nahid, Payam ^{[1
,2
]}

Kim, Peter S. ^{[3
]}

Evans, Carlton A. ^{[4
,5
]}

Alland, David ^{[6
]}

Barer, Michael ^{[7
]}

Diefenbach, Jane ^{[8
]}

Ellner, Jerrold ^{[9
]}

Hafner, Richard ^{[3
]}

Hamilton, Carol Dukes ^{[10
]}

Iademarco, Michael F. ^{[14
]}

Ireton, Gregory ^{[11
]}

Kimerling, Michael E. ^{[12
]}

Lienhardt, Christian ^{[13
]}

MacKenzie, William R. ^{[14
]}

Murray, Megan ^{[15
]}

Perkins, Mark D. ^{[16
]}

Posey, Jamie E. ^{[14
]}

Roberts, Teri ^{[17
]}

Sizemore, Christine ^{[18
]}

Stevens, Wendy S. ^{[19
,20
]}

Via, Laura ^{[21
]}

Williams, Sharon D. ^{[3
]}

Yew, Wing W. ^{[22
]}

Swindells, Susan ^{[23
]}

机构：

[1] Univ Calif San Francisco, San Francisco Gen Hosp, Dept Med, Div Pulm & Crit Care Med, San Francisco, CA 94110 USA

[2] Univ Calif San Francisco, Curry Int TB Ctr, San Francisco, CA 94110 USA

[3] NIAID, Div Aids, Bethesda, MD 20892 USA

[4] Univ Peruana Cayetano Heredia, IFHAD, Lima, Peru

[5] Univ London Imperial Coll Sci Technol & Med, Dept Infect Dis & Immun, London SW7 2AZ, England

[6] Univ Med & Dent New Jersey, Dept Med, Ctr Emerging & Reemerging Pathogens, Newark, NJ 07103 USA

[7] Univ Leicester, Dept Infect Immun & Inflammat, Leicester LE1 7RH, Leics, England

[8] PharmaStat LLC, Newark, CA USA

[9] Boston Univ Sch Med & Med Ctr, Dept Med, Infect Dis Sect, Boston, MA USA

[10] Family Hlth Int, Durham, NC USA

[11] Bill & Melinda Gates Fdn, Infect Dis Res Inst, Seattle, WA USA

[12] Bill & Melinda Gates Fdn, Global Hlth Program, Seattle, WA USA

[13] WHO, Stop TB Partnership, CH-1211 Geneva, Switzerland

[14] Ctr Dis Control & Prevent, Div TB Eliminat, Atlanta, GA USA

[15] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA

[16] Fdn Innovat New Diagnost, Geneva, Switzerland

[17] Med San Frontieres, Campaign Access Essential Med, Geneva, Switzerland

[18] NIAID, Div Microbiol & Infect Dis, Bethesda, MD 20892 USA

[19] Univ Witwatersrand, Johannesburg, South Africa

[20] Natl Hlth Lab Serv, Johannesburg, South Africa

[21] NIAID, Lab Clin Infect Dis, TB Res Sect, Bethesda, MD 20892 USA

[22] Hong Kong TB Chest & Heart Dis Assoc, Hong Kong, Hong Kong, Peoples R China

[23] Univ Nebraska Med Ctr, Dept Internal Med, Omaha, NE USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 2012年 / 205卷

基金：

英国惠康基金;

关键词：

MEDIATED ISOTHERMAL AMPLIFICATION; DRUG-SUSCEPTIBILITY ASSAY; SPUTUM SMEAR MICROSCOPY; MYCOBACTERIUM-TUBERCULOSIS; PULMONARY TUBERCULOSIS; RESISTANT TUBERCULOSIS; MOLECULAR-DETECTION; LAM-ELISA; URINE; ACCURACY;

D O I：

10.1093/infdis/jis194

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The development, evaluation, and implementation of new and improved diagnostics have been identified as critical needs by human immunodeficiency virus (HIV) and tuberculosis researchers and clinicians alike. These needs exist in international and domestic settings and in adult and pediatric populations. Experts in tuberculosis and HIV care, researchers, healthcare providers, public health experts, and industry representatives, as well as representatives of pertinent US federal agencies (Centers for Disease Control and Prevention, Food and Drug Administration, National Institutes of Health, United States Agency for International Development) assembled at a workshop proposed by the Diagnostics Working Group of the Federal Tuberculosis Taskforce to review the state of tuberculosis diagnostics development in adult and pediatric populations.

引用

页码：S159 / S168

页数：10

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