Hfq Regulates Biofilm Gut Blockage That Facilitates Flea-Borne Transmission of Yersinia pestis

被引:38
|
作者
Rempe, Katherine A.
Hinz, Angela K.
Vadyvaloo, Viveka [1 ]
机构
[1] Washington State Univ, Paul G Allen Sch Global Anim Hlth, Pullman, WA 99164 USA
关键词
RNA CHAPERONE HFQ; OUTER-MEMBRANE; BACTERIAL COMMUNITIES; ESCHERICHIA-COLI; NONCODING RNAS; VIRULENCE; PLAGUE; PSEUDOTUBERCULOSIS; VECTOR; GENES;
D O I
10.1128/JB.06568-11
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The plague bacillus Yersinia pestis can achieve transmission by biofilm blockage of the foregut proventriculus of its flea vector. Hfq is revealed to be essential for biofilm blockage formation and acquisition and fitness of Y. pestis during flea gut infection, consistent with posttranscriptional regulatory mechanisms in plague transmission.
引用
收藏
页码:2036 / 2040
页数:5
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