Recent advances in the monitoring, modelling and control of crystallization systems

被引：250

作者：

Nagy, Zoltan K. ^{[1
,2
]}

Fevotte, Gilles ^{[3
]}

Kramer, Herman ^{[4
]}

Simon, Levente L. ^{[5
]}

机构：

[1] Purdue Univ, Sch Chem Engn, W Lafayette, IN 47907 USA

[2] Univ Loughborough, Dept Chem Engn, EPSRC Ctr Innovat Mfg Continuous Mfg & Crystallis, Loughborough LE11 3TU, Leics, England

[3] Univ Lyon 1, Sch Mines St Etienne, F-69365 Lyon, France

[4] Delft Univ Technol, Proc & Energy Lab, NL-2628 CA Delft, Netherlands

[5] BASF Schweiz AG, CH-4133 Schweizerhalle, Switzerland

来源：

CHEMICAL ENGINEERING RESEARCH & DESIGN | 2013年 / 91卷 / 10期

基金：

欧洲研究理事会;

关键词：

Population balance modelling; Process analytical technologies; Crystallization modelling; Crystallization monitoring; Crystallization control; Crystallization review; CRYSTAL-SIZE DISTRIBUTION; BATCH-COOLING CRYSTALLIZATION; DIRECT NUCLEATION CONTROL; METASTABLE ZONE WIDTH; L-GLUTAMIC ACID; PROCESS ANALYTICAL TECHNOLOGY; POPULATION BALANCE-EQUATIONS; BEAM REFLECTANCE MEASUREMENT; ANALYTE SIGNAL NAS; PARTICLE-SIZE;

D O I：

10.1016/j.cherd.2013.07.018

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Crystallization is one of the most important unit operations used for the separation and purification of crystalline solid products. Appropriate design and control of the crystallization process is paramount to produce crystalline products with tailor-made-properties. This paper provides an overview of selected recent developments in the modelling, monitoring and control of crystallization processes. We consider the topics discussed in this review to be enabling technologies for the development of the next generation of crystallization processes with significantly improved predictability, robustness and controllability. (C) 2013 The Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.

引用

页码：1903 / 1922

页数：20

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