Anthropometric measurements and survival after a prostate cancer diagnosis

被引:20
|
作者
Farris, Megan S. [1 ]
Courneya, Kerry S. [2 ]
Kopciuk, Karen A. [1 ,3 ,4 ]
McGregor, S. Elizabeth [3 ,5 ,6 ]
Friedenreich, Christine M. [1 ,3 ,6 ]
机构
[1] Holy Cross Ctr, Alberta Hlth Serv, CancerControl Alberta, Dept Canc Epidemiol & Prevent Res, Calgary, AB, Canada
[2] Univ Alberta, Fac Phys Educ & Recreat, Edmonton, AB, Canada
[3] Univ Calgary, Cumming Sch Med, Dept Oncol, Calgary, AB, Canada
[4] Univ Calgary, Dept Math & Stat, Calgary, AB, Canada
[5] Alberta Hlth Serv, Populat Publ & Indigenous Hlth, Calgary, AB, Canada
[6] Univ Calgary, Cumming Sch Med, Dept Community Hlth Sci, Calgary, AB, Canada
关键词
anthropometrics; obesity; prostate cancer; survival; mortality; PHYSICAL-ACTIVITY; OBESITY; RISK; RESIDUALS; MORTALITY; MODELS;
D O I
10.1038/bjc.2017.440
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Evidence regarding the role of anthropometrics in prostate cancer survival is inconsistent. We examined the associations between anthropometric measures and survival outcomes. Methods: Men diagnosed with prostate cancer (n = 987) were recruited into a population-based case-control study between 1997 and 2000, then a prospective cohort study between 2000 and 2002, where anthropometric measurements (weight, height, body mass index, waist circumference, waist-hip ratio) were taken and participants were followed up to 19 years for survival outcomes. Cox proportional hazards were used to examine these associations. Results: Survival analyses suggested no clear pattern of associations between post-diagnosis anthropometric measurements and all-cause mortality, prostate-specific mortality, first recurrence/progression or new primary cancer. Conclusions: We did not find a significant trend relating anthropometrics to survival outcomes after prostate cancer diagnosis. Continued assessment of objective measurements of body composition over the life-course is warranted to determine true associations between anthropometrics and survival after prostate cancer.
引用
收藏
页码:607 / 610
页数:4
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