Precise measurement of the activity of 186Re, 188Re radiopharmaceuticals

被引:19
|
作者
Sahagia, M [1 ]
Razdolescu, AC [1 ]
Grigorescu, EL [1 ]
Luca, A [1 ]
Ivan, C [1 ]
机构
[1] IFIN HH, Natl Inst R&D Phys & Nucl Engn Horia Hulubei, RO-76900 Bucharest, Romania
关键词
Re-186; Re-188; radiopharmaceuticals; standardization; detection efficiency; ionization chamber; calibration;
D O I
10.1016/S0969-8043(01)00213-5
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The paper presents the results obtained in the assurance of traceability along the whole chain: production, distribution, use in hospitals, for the activity measurement of radiopharmaceuticals containing (186) Re, Re-188 and Re-186+Re-188 mixtures. Standardization of the solutions, 4piPC-beta-efficiency relations and responses of a Centronic IG 12/20A ionization chamber and other radioisotope calibrators are presented. Gamma-ray and bremsstrahlung radiation contributions in the total response were evaluated. Some of the relevant results were compared with literature data. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:349 / 356
页数:8
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