Mode of action of ticagrelor at the human platelet P2Y12-receptor

被引:0
|
作者
Hoffmann, K. [1 ]
von Kuegelgen, I [1 ]
机构
[1] Univ Bonn, Inst Pharmakol & Toxikol, D-53127 Bonn, Germany
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
138
引用
收藏
页码:S36 / S36
页数:1
相关论文
共 50 条
  • [21] Switching P2Y12-receptor inhibitors in patients with coronary artery disease
    Fabiana Rollini
    Francesco Franchi
    Dominick J. Angiolillo
    Nature Reviews Cardiology, 2016, 13 : 11 - 27
  • [22] Involvement of basic amino acid residues in transmembrane regions 6 and 7 in agonist and antagonist recognition of the human platelet P2Y12-receptor
    Hoffmann, Kristina
    Sixel, Uta
    Di Pasquale, Francesca
    von Kuegelgen, Ivar
    BIOCHEMICAL PHARMACOLOGY, 2008, 76 (10) : 1201 - 1213
  • [23] Ticagrelor inhibits human platelet aggregation via adenosine in addition to P2Y12 antagonism
    Nylander, S.
    Femia, E. A.
    Scavone, M.
    Berntsson, P.
    Asztely, A. -K.
    Nelander, K.
    Lofgren, L.
    Nilsson, R. G.
    Cattaneo, M.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2013, 11 (10) : 1867 - 1876
  • [24] THERAPEUTIC WINDOW FOR P2Y12-RECEPTOR INHIBITION: A COLLABORATIVE ANALYSIS OF THE RELATION BETWEEN PLATELET REACTIVITY, STENT THROMBOSIS AND BLEEDING
    Aradi, Daniel
    Bonello, Laurent
    Kirtane, Ajay
    Kastrati, Adnan
    Stone, Gregg
    Sibbing, Dirk
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2015, 65 (10) : A13 - A13
  • [25] Pharmacology of the platelet P2Y12 receptor
    von Kuegelgen, Ivar
    PURINERGIC SIGNALLING, 2018, 14 : S8 - S9
  • [26] P2Y12 receptor in platelet activation
    Kim, Soochong
    Kunapuli, Satya P.
    PLATELETS, 2011, 22 (01) : 56 - 60
  • [27] Platelet-related biomarkers and their response to inhibition with aspirin and p2y12-receptor antagonists in patients with acute coronary syndrome
    Angela Lowenstern
    Robert F. Storey
    Megan Neely
    Jie-Lena Sun
    Dominick J. Angiolillo
    Christopher P. Cannon
    Anders Himmelmann
    Kurt Huber
    Stefan K. James
    Hugo A. Katus
    Joao Morais
    Agneta Siegbahn
    Phillippe Gabriel Steg
    Lars Wallentin
    Richard C. Becker
    Journal of Thrombosis and Thrombolysis, 2017, 44 : 145 - 153
  • [28] Platelet-related biomarkers and their response to inhibition with aspirin and p2y12-receptor antagonists in patients with acute coronary syndrome
    Lowenstern, Angela
    Storey, Robert F.
    Neely, Megan
    Sun, Jie-Lena
    Angiolillo, Dominick J.
    Cannon, Christopher P.
    Himmelmann, Anders
    Huber, Kurt
    James, Stefan K.
    Katus, Hugo A.
    Morais, Joao
    Siegbahn, Agneta
    Steg, Phillippe Gabriel
    Wallentin, Lars
    Becker, Richard C.
    JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 2017, 44 (02) : 145 - 153
  • [29] Ticagrelor binds to human P2Y12 independently from ADP but antagonizes ADP-induced receptor signaling and platelet aggregation
    van Giezen, J. J. J.
    Nilsson, L.
    Berntsson, P.
    Wissing, B. -M.
    Giordanetto, F.
    Tomlinson, W.
    Greasley, P. J.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 (09) : 1556 - 1565
  • [30] Impact of Reticulated Platelets on the Antiplatelet Effect of the Intravenous P2Y12-Receptor Inhibitor Cangrelor
    Stratz, Christian
    Nuehrenberg, Thomas
    Valina, Christian M.
    Loeffelhardt, Nikolaus
    Mashayekhi, Kambis
    Ferenc, Miroslaw
    Trenk, Dietmar
    Neumann, Franz-Josef
    Hochholzer, Willibald
    THROMBOSIS AND HAEMOSTASIS, 2018, 118 (02) : 362 - 368